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[ST12-13(2P-275)]6-shogaol a Component of Ginger, Significantly Ameliorated Pressure Overload-induced Systolic Dysfunction through the inhibition of p300 Histone Acetyltransferase Activity

Yuto Kawase1, Kana Shimizu1,2, Masafumi Funamoto1,2, Yoichi Sunagawa1,2,3, Yasufumi Katanasaka1,2,3, Toshihide Hamabe1,2,3, Satoshi Shimizu1,2, Ryuya Naruta1, Maki Komiyama2, Philip Howke4, Koji Hasegawa1,2, Tatsuya Morimoto1,2,3 (1.Division of Molecular Medicine, Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, 2.Clinical Research Institute, Kyoto Medical Center, National Hospital Organization, 3.Shizuoka General Hospital, 4.Laboratory of Scientific English, School of Pharmaceutical Sciences, University of Shizuoka)

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