APPW2025

Oranizers :Yuhei Nishimura (Department of Integrative Pharmacology, Mie University Graduate School of Medicine) and Masaki Saito (Department of Molecular Physiology and Pathology, School of Pharma-Sciences, Teikyo University)

The primary cilium, an antenna-like structure of the plasma membrane, works as the signaling hub to sense the stimuli through receptors and channels localized in the cilia and to transduce the signals into the cells. Recent advances in anatomy, physiology, and pharmacology have revealed how primary cilia regulate physiological functions and how dysregulation of primary cilia can cause diseases. These findings have boosted the efforts to develop novel therapeutic approaches targeting primary cilia. The scope of this symposium is to integrate the current knowledge and opinions of primary cilia about their potential as therapeutic targets.