[2S12m] Organelle-orchestrated multi-mode physiology | APPW2025

Session Details

Symposium

[2S12m]Organelle-orchestrated multi-mode physiology

Tue. Mar 18, 2025 8:30 AM - 10:20 AM JST
Tue. Mar 18, 2025 11:30 PM - 1:20 AM UTC

Room 12

Oranizers :Sho Aki (Division of Integrative Nutriomics and Oncology, RCAST, The University of Tokyo) and Daisuke Shimura (The University of Utah, School of Medicine, Department of Surgery & Nora Eccles Harrison Cardiovascular Research and Traing Institute (CVRTI))

Organelles, one of the characteristics of eukaryotic cells, not only function as "containers" for biological substances and enzymes, but also dynamically change their morphology and localization to control cellular functions. Recently, it has become clear that organelles play important roles not only in intracellular regulation but also in biological homeostasis. Therefore, new physiological research fields are developing from conventional biological physiology to the analysis of multicellular interactions or organelle-level interactions that cannot be elucidated by single-cell analysis. At this symposium, young researchers in various fields will gather and introduce their research about Organelle-orchestrated multi-mode physiology. This symposium will also provide an opportunity for new researchers to enter the field.

8:33 AM - 8:54 AM JST(11:33 PM - 11:54 PM UTC)

[2S12m-1]Mitochondria dynamics and protection by interaction between actin cytoskeleton and small isoform of gap junction protein, GJA1-20k

^○Daisuke Shimura^1,2, Mario Maalouf¹, Vu Nguyen¹, Adelaide Gaffney¹, Bridger Bell¹, Jennifer Hunter¹, Robin Shaw¹ (1.The University of Utah, 2.Institute of Science Tokyo)

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8:54 AM - 9:15 AM JST(11:54 PM - 12:15 AM UTC)

[[OD]2S12m-2]Critical role of Lama4 for hematopoiesis regeneration and acute myeloid leukemia progression

^○Makoto Kondo^1,2,3 (1.Institute of Industrial Science, The University of Tokyo, 2.Dept. Bioengineering, School of Engineering, The University of Tokyo, 3.Dept. Molecular Pharmaceutics, College of Pharmacy, The University of Utah)

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9:15 AM - 9:36 AM JST(12:15 AM - 12:36 AM UTC)

[[OD]2S12m-3]Novel immune evasion mechanisms involving mitochondria transfer in the tumor microenvironment

^○Hideki Ikeda^1,2, Masahito Kawazu¹, Yosuke Togashi^1,3,4 (1.Division of Cell Therapy, Chiba Cancer Center Research Institute, 2.Department of Respirology, Graduate School of Medicine, Chiba University, 3.Department of Tumor Microenvironment, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 4.Department of Allergy and Respiratory Medicine, Okayama University Hospital)

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9:36 AM - 9:57 AM JST(12:36 AM - 12:57 AM UTC)

[[OD]2S12m-4]Peroxisome-orchestrated multimode physiology

^○Ayumu Sugiura¹, Junji Yamaguchi¹, Isei Tanida¹, Yasuo Uchiyama¹, Hikari Taka¹, Yoshiki Miura¹, YuhKoh Satouh², Ken Sato², Shohei Ucinomiya³, Toshihiko Fujimori⁴, Yasusi Okazaki^1,5 (1.Juntendo University, 2.Institute for Molecular and Cellular Regulation, Gunma University, 3.Graduate School of Pharmaceutical Sciences, Kyushu University, 4.Division of Embryology, National Institute for Basic Biology, 5.RIKEN Center for Integrative Medical Sciences)

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9:57 AM - 10:18 AM JST(12:57 AM - 1:18 AM UTC)

[[OD]2S12m-5]Organelle metabolic crosstalk orchestrated multi-mode physiology

^○Sho Aki, Tsuyoshi Osawa (Division of Integrative Nutriomics and OncologyRCAST, The University of Tokyo)

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