Session Details
[3S07a]Glial function in controlling brain structure and function from micro to macro scale
Wed. Mar 19, 2025 1:40 PM - 3:30 PM JST
Wed. Mar 19, 2025 4:40 AM - 6:30 AM UTC
Wed. Mar 19, 2025 4:40 AM - 6:30 AM UTC
Room 7
Oranizers :Schuichi Koizumi (Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi) and Misa Arizono (The Hakubi Center for Advanced Research/Graduate School of Medicine, Kyoto University)
The brain is considered an organ in which neurons connect with each other via synapses to form an enormous neural network. While the mechanisms within neurons are crucial for the construction and function of this vast neural network, the importance of the role played by surrounding non-neuronal cells, known as glial cells, has been increasingly highlighted. Glial cells make contact with synapses and are responsible for the formation and elimination of synapses. During brain development, glial cells also change in their number and contribute to cerebral gyrus formation. In other words, glial cells are increasingly being recognized as key controllers of the brain's morphology and function, spanning from the micro to the macro level. This symposium aims to deepen the understanding of the function of glial cells for brain function and structure at micro- and microscopic levels. To do this, we have four emerging researchers who lead this field and present recent findings with the latest techniques including imaging and manipulation of cellular functions.
[[OD]3S07a-1]Evolutionary changes of astrocytes in mammalian brains
○Yohei Shinmyo1, Hiroshi Kawasaki2 (1.Department of Neurophysiology Hamamatsu University School of Medicine, 2.Department of Medical Neuroscience Kanazawa University)
[[OD]3S07a-2]New perspectives on the regulation of cognitive function with oligodendrocytes and their progenitor cells
○Daisuke Kato (Department of Physiology, Nippon Medical School Graduate School of Medicine)
[3S07a-3]Structural physiology of astrocytes unveiled by lattice light sheet microscopy
○Misa Arizono1, Valentin Nägerl2 (1.Graduate school of medicine/Hakubi Center, Kyoto university, 2.Institute of Anatomy and Cell Biology, University Medical Center Göttingen)
[[OD]3S07a-4]Neuronal excitability regulated by disease-relevant upregulation of Gq-GPCR pathway in astrocytes.
○Eiji Shigetomi1,2, Schuichi Koizumi1,2 (1.Yamanashi GLIA center, Univ Yamanashi, 2.Dept Neuropharmacol, Interdiscipl Grad Sch Med, Univ Yamanashi)