[1A-3] Medical Bio

1:40 PM - 2:00 PM JST(4:40 AM - 5:00 AM UTC)

[1A-3-03] Synthesis and functional characterization of astatine-211 labeled peptides and evaluation of cellular effects for targeted alpha radionuclide therapy using astatine-211

*Masayuki Takamatsu^1,2, Jumpei Ueno¹, Koki Mayusumi^1,2, Taketo Toda¹, Atsushi Shimoyama^1,2, Kazuya Kabayama^1,2, Tadashi Watabe^2,3, Kazuko Nakashima Kaneda^1,2, Yoshifumi Shirakami², Yuichiro Kadonaga², Taku Yoshiya⁴, Masashi Murakami², Kazuhiro Ooe², Atsushi Toyoshima², Hiromitsu Haba⁵, Jens Cardinale⁶, Frederik Giesel⁶, Koichi Fukase^1,2 (1. Graduate School of Science, The University of Osaka, 2. Institute for Radiation Sciences, The University of Osaka, 3. Graduate School of Medicine, The University of Osaka, 4. Peptide Institute, Inc., 5. RIKEN, 6. University Hospital Düsseldorf)

Keywords:

Targeted alpha therapy,astatine-211,Fibroblast activation proteins,nuclear medicine,Biodistribution