[1B-3] nucleic acid-related

1:20 PM - 1:40 PM JST(4:20 AM - 4:40 AM UTC)

[1B-3-02] Controlling and Utilizing Toxic Gapmer-ASOs: Cytotoxicity Mitigation via Acyclic Artificial Nucleic Acids and Cell Death Induction using DNA Logic Circuits

*Jumpei Ariyoshi¹, Masaya Higuchi², Mioka Okuno¹, Nozomi Tanigawa¹, Otsuka Ayano¹, Manaka Yamaoka¹, Aki Tsumura¹, Yuka Suzumura¹, Koji Yamashita¹, Masayuki Okada¹, Oyama Hiroyuki¹, Hiroyuki Asanuma², Yukiko Kamiya^1,2 (1. Kobe Pharmaceutical University, 2. Graduate School of Engineering, Nagoya University)

Keywords:

Nucleic Acid Therapeutics,Gapmer-ASO,DNA logic gate