[1P] Poster presentation 1P even number

[1P-024] A chemogenetic approach targeting adenosine A_2A receptors for tunable regulation of CAR-T cell antitumor activity

*Shinichi OKI¹, Yuma MATSUOKA¹, Tomohiro DOURA¹, Shiho HIRANO², Hidetsugu ASADA³, So IWATA^3,4, Seitaro TERAKURA², Shigeki KIYONAKA^1,5 (1. Graduate School of Engineering, Nagoya University, 2. Graduate School of Medicine, Nagoya University, 3. Graduate School of Medicine, Kyoto University, 4. Graduate School of Biostudies, Kyoto University, 5. Research Institute for Quantum and Chemical Innovation, Nagoya University)

Keywords:

CAR-T cell,Solid tumor,Adenosine A2A Receptor (A2AR),Chemogenetics,GPCR,Tumormicroenvironment,Immune checkpoint