The 20th Symposium on Biorelevant Chemistry
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Session Details

Oral : DDS, Medical Bio

[3B-2]DDS, Medical Bio

Sat. Sep 12, 2026 10:30 AM - 11:50 AM JST
Sat. Sep 12, 2026 1:30 AM - 2:50 AM UTC
Hall B(Large Conference Room)
Chair:Masafumi Minoshima(The University of Osaka), Takeshi Mori(Kyushu University)
10:30 AM - 10:50 AM JST(1:30 AM - 1:50 AM UTC)

[3B-2-01]SB-mtDirect : Mitochondrial delivery of proteins by sulfobetaine polymer conjugation

*Nobuyuki Morimoto1, Yoshihiro Kawai1, Sayaka Toita1, Reiko Ishihara2, Takaya Ishihara2 (1. Faculty of Materials for Energy, 2. School of Medicine)
10:50 AM - 11:10 AM JST(1:50 AM - 2:10 AM UTC)

[3B-2-02]Development of an albumin-binding Fe(III) complex with a proton-exchange mechanism for tumor MR imaging

*Satoshi Okada1,2, Gakuto Oki2, Martina Sanadar3, Shunya Kitahara2, Megumi Iiyama4, Akira Sumiyoshi4, Hiroyuki Nakamura1,2, Célia S. Bonnet3 (1. Institute of Integrated Research, Institute of Science Tokyo, 2. School of Life Science and Technology, Institute of Science Tokyo, 3. Centre national de la recherche scientifique, 4. National Institutes for Quantum Science and Technology)
11:10 AM - 11:30 AM JST(2:10 AM - 2:30 AM UTC)

[3B-2-03]Enhancing PROTAC Membrane Permeability by Combining Amide-to-Ester Substitution and Linker Methylation Strategies

*Mazin Abdelwahid1, Eisuke Hayakawa1, Keigo Hirai1, Mayumi Ishii2, Kayoko Kanamitsu2, Saori Yasuda1, Fumiaki Ohtake3,4, Shinichi Sato1,5, Shusuke Tomoshige1, Minoru Ishikawa1 (1. Graduate School of Life Sciences, Tohoku University, 2. Drug Discovery Initiative, The University of Tokyo, 3. School of Pharmacy and Pharmaceutical Sciences, Hoshi University, 4. Institute for Advanced Life Sciences, Hoshi University, 5. Frontier Research Institute for Interdisciplinary Sciences, Tohoku University)
11:30 AM - 11:50 AM JST(2:30 AM - 2:50 AM UTC)

[3B-2-04]Visualization of Hypoxic Response Regions in Three-Dimensional Cultured Spheroids Using Reporter Cells

*Nozomu Koiwa1, Yoshinobu Utagawa3, Hiroya Abe1,2, Norio Suzuki3, Koh Nakayama4, Shusuke Taniuchi4, Hitoshi Shiku1, Kosuke Ino1 (1. Graduate School of Engineering, Tohoku University, 2. Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, 3. New Industry Creation Hatchery Center, Tohoku University, 4. Faculty of Medicine, Asahikawa Medical University)
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