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[H931-3am-09]Synthesis and properties of antisense oligonucleotides containing 4'-C-(N-alkyl)aminoethyl thymidines.

○Kota Fujiki1,5, Yoshihito Ueno1,2,3,4 (1. The Graduate School of Natural Science and Technology, Gifu University, 2. Faculty of Applied Biological Science, Gifu University, 3. The United Graduate School of Agricultural Science, Gifu Univercity, 4. Center for One Medicine Innovative Translational Reseach(COMIT), Gifu university Institute for Advanced Study, Gifu University, 5. Convolution of Informatics and Biomedical Sciences on Glocal Alliances, CIBoG)
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Keywords:

Nucleic acid therapeutics,Antisense oligonucleotides,Chemical modification,Amino alkyl