Session Details
[H931-3am]17. Biofunctional Chemistry, Biotechnology
Wed. Mar 20, 2024 9:00 AM - 11:40 AM JST
Wed. Mar 20, 2024 12:00 AM - 2:40 AM UTC
Wed. Mar 20, 2024 12:00 AM - 2:40 AM UTC
H931(931, Bldg. 9 [3F])
Chair: Yasuaki Kimura, Yoshiaki Masaki
[H931-3am-01]Chemical synthesis of rare sugar-derived nucleosides
○Yutaka Narita1, Natsuhisa Oka1,2,3 (1. Fac. of Eng., Gifu Univ., 2. iGCORE, Gifu Univ., 3. COMIT, Gifu Univ.)
[H931-3am-02]Post-modification of nucleic acids with amino acids via a ciano group
○Takumi Yoshida1, Natsuhisa Oka1,2,3 (1. Fac. of Eng., Gifu Univ., 2. iGCORE, Gifu Univ., 3. COMIT, Gifu Univ.)
[H931-3am-03]Development of chemoselective condensation reaction of nucleoside 3'-H-phosphonothioate
○Harumi Okutsu1, Yuhei Takahashi1, Kazuki Sato1, Takeshi Wada1 (1. Tokyo University of Science)
[H931-3am-04]Development of purity assay method of boranophosphate DNAs by using PB/PO conversion reaction
○Kentaro matsumoto1, Yuhei Takahashi1, Kazuki Sato1, Wada Takeshi1 (1. Tokyo university of science)
[H931-3am-05]Photoreactivity of psoralens and trioxsalens for DNA duplexes
○Kazuhisa Fujimoto1, Amin Md Al2, Takanori Oyoshi2 (1. Kyushu Sangyo University, 2. Shizuoka University)
[H931-3am-06]Interstrand Crosslinks using Oligonucleotides Containing 2’-Deoxythioguanosine
○Jamila Abbas Osman1,2, Kazumitsu Onizuka1,2, Yuuhei Yamano1,2, Ahmed Mostafa Abdelhady1,2, Fumi Nagatsugi1,2 (1. Graduate school of science, Department of Chemistry, Tohoku University, 2. Institute of Multidisciplinary Research for Advanced Materials, Tohoku University)
[H931-3am-07]Development and Comparison of 4-Thiouridine to Cytidine Chemical Base Conversion Reaction
○Sana Ohashi1, Mayu Nakamura1, Susit Archaryya1, Masahito Inagaki1, Naoko Abe1, Yasuaki Kimura1, Fumitaka Hashiya2,3, Hiroshi Abe1,2,3,4 (1. Graduate School of Science, Nagoya Univ., 2. Research Center for Material Science, Nagoya Univ., 3. CREST, Japan Science and Technology Agency, 4. Institute for Glyco-core Research (iGCORE), Nagoya Univ.)
[H931-3am-08]Enzymatic incorporation and extension studies of the unnatural alkynylated purine-pyridazine base pair
○Wenjue Fan1,2, Hidenori Okamura1,2, Zhuoxin Dong1,2, Giang Hoang Trinh1,2, Fumi Nagatsugi1,2 (1. IMRAM, Tohoku Univ., 2. Grad. Sch. Sci., Tohoku Univ.)
Break
[H931-3am-09]Synthesis and properties of antisense oligonucleotides containing 4'-C-(N-alkyl)aminoethyl thymidines.
○Kota Fujiki1,5, Yoshihito Ueno1,2,3,4 (1. The Graduate School of Natural Science and Technology, Gifu University, 2. Faculty of Applied Biological Science, Gifu University, 3. The United Graduate School of Agricultural Science, Gifu Univercity, 4. Center for One Medicine Innovative Translational Reseach(COMIT), Gifu university Institute for Advanced Study, Gifu University, 5. Convolution of Informatics and Biomedical Sciences on Glocal Alliances, CIBoG)
[H931-3am-10]Synthesis of 4'-C-aminoethoxy-2'-O-methyl-5-propynyluridine and its application for antisense oligonucleotide
○Yujun Zhou1,4, Yoshihito Ueno1,2,3,5 (1. The United Graduate School of Agriculture Science (UGSAS), Gifu University, 2. Faculty of Applied Biological Sciences, Gifu University, 3. Graduate School of Natural Sciences and Technology, Gifu Unviversity, 4. Convolution of Informatics and Biomedical Sciences on Glocal Alliances (CIBoG), Nagoya University, 5. Center for One Medicine Innovative Translational Research (COMIT), Tokai National Higher Education and Research System)
[H931-3am-11]Synthesis and evaluation of a thymidine dimer with an extended backbone at five prime position
○Shigetoshi Tachibana1, Rie Ohnishi1, Yoshiaki Masaki1, Kohji Seio1 (1. Sch. Life Sci. Tech., Tokyo Tech.)
[H931-3am-12]Synthesis of 5-methyluridine derivatives with sulfonamide or sulfonate modifications on the 2´ hydroxyl group and evaluation of their ability to form duplex chains
○Shuntaro Takigawa1, Takahito Tomori1, Koya Uekusa1, Yoshiaki Masaki1, Kohji Seio1 (1. Sch. Life Sci. Tech., Tokyo Tech.)
[H931-3am-13]Synthesis and properties of oligonucleotides having substituted 2´-O, 3´-C-bridged [3.2.0]bicycloarabinonucleoside
○Ayano P Tabira1, Shunsuke Wakatsuki1, Kohji Seio1, Yoshiaki Masaki1 (1. Sch. Life Sci. Tech., Tokyo Tech.)
[H931-3am-14]Synthesis and Evaluation of Photolabile Selenium-Modified Nucleic Acid for Intracellular Gene Expression Switching
○Yuki Yoshida1, Haruka Hiraoka1, Hirotaka Murase1,2, Naoko Abe1, Fumitaka Hashiya3, Hiroshi Abe1,4,5 (1. Graduate School of Science, Nagoya University, 2. Department of Pharmacy, Sojo University, 3. Research Center for Materials Science, Nagoya University, 4. JST-CREST, 5. Institute for Glyco-core Research)
[H931-3am-15]Construction of Chimeric Artificial Nucleic Acids (CANA) forward Inhibition of Pancreatic Cancer Transcription Factor BACH1 ⅠV: - Effects of Junction Position on Complex Stability and Cleavage Efficiency -
○Yuki Igarashi1, Yuto Horiuchi1, Mitsuyo Matsumoto2, Yu Mikame3, Masaki Nishijima1, Yasuyuki Araki1, Asako Yamayoshi3, Kazuhiko Igarashi2, Takehiko Wada1 (1. Institute of Multidisciplinary Research for Advanced Materials (IMRAM), Tohoku University, 2. Graduate School of Medicine, Tohoku University, 3. Graduate School of Biomedical Sciences, Nagasaki University)