Presentation Information

10:40 AM - 10:50 AM JST(1:40 AM - 1:50 AM UTC)Japanese

[H931-3am-10]Synthesis of 4'-C-aminoethoxy-2'-O-methyl-5-propynyluridine and its application for antisense oligonucleotide

○Yujun Zhou^1,4, Yoshihito Ueno^1,2,3,5 (1. The United Graduate School of Agriculture Science (UGSAS), Gifu University, 2. Faculty of Applied Biological Sciences, Gifu University, 3. Graduate School of Natural Sciences and Technology, Gifu Unviversity, 4. Convolution of Informatics and Biomedical Sciences on Glocal Alliances (CIBoG), Nagoya University, 5. Center for One Medicine Innovative Translational Research (COMIT), Tokai National Higher Education and Research System)

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Keywords:

Oligonucleotide therapeutics,Antisense oligonucleotide,Chemical modification,Amino alkyl group,Propynyl group

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