[H931-3am] 17. Biofunctional Chemistry, Biotechnology

11:30 AM - 11:40 AM JST(2:30 AM - 2:40 AM UTC)Japanese

[H931-3am-15] Construction of Chimeric Artificial Nucleic Acids (CANA) forward Inhibition of Pancreatic Cancer Transcription Factor BACH1 ⅠV: - Effects of Junction Position on Complex Stability and Cleavage Efficiency -

○Yuki Igarashi¹, Yuto Horiuchi¹, Mitsuyo Matsumoto², Yu Mikame³, Masaki Nishijima¹, Yasuyuki Araki¹, Asako Yamayoshi³, Kazuhiko Igarashi², Takehiko Wada¹ (1. Institute of Multidisciplinary Research for Advanced Materials (IMRAM), Tohoku University, 2. Graduate School of Medicine, Tohoku University, 3. Graduate School of Biomedical Sciences, Nagasaki University)

Keywords:

Oligonucleotide Therapeutics,Chimeric Artificial Nucleic Acids,Catalytic Cleavage of Target RNA,Pancreatic Cancer,BACH1