16th JBF Symposium
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Session Details

Poster Presentation

[P3]Poster Presentation

Wed. Mar 5, 2025 10:45 AM - 11:45 AM JST
Wed. Mar 5, 2025 1:45 AM - 2:45 AM UTC
Poster Session(1st floor)
10:45 AM - 11:45 AM JST(1:45 AM - 2:45 AM UTC)

[P3-01]Multi-laboratory study of LC/MS method development for the quantification of cyclorasin 9A5 in plasma

*Rika Ishikawa1, Kosuke Saito1, Mikio Shirasaki2, Koichi Shiga2, Koichiro Hotta3, Kiyomi Kikuchi3, Ryoma Yamamoto4, Kentaro Takahara4, Takuma Shigeyama5, Risa Hamada5, Hisashi Fujita6, Masaaki Kakehi6, Masayoshi Saito7, Yukiko Sugawara7, Yuki Kishino8, Hitomi Shimoda8, Ryoya Goda9, Yoshiro Saito1, Ruri Kikura-Hanajiri1 (1. National Institute of Health Sciences, 2. Axcelead Drug Discovery Partners, Inc., 3. Eisai Co., Ltd., 4. Thermo Fisher Scientific, 5. Sumika Chemical Analysis Service, Ltd., 6. Takeda Pharmaceutical Co., Ltd., 7. Mitsubishi Tanabe Pharma Corporation, 8. Daiichi Sankyo Co., Ltd., 9. Future Peak)

[P3-02]Multicenter validation of quantification methods for adeno-associated virus vector in biological samples using digital PCR and quantitative PCR

*Yoichi Tanaka1, Ryosuke Ide2, Kyoko Watanabe3, Kosuke Shimada4, Hiroshi Katsumoto4, Hiroyuki Ichida5, Kazuhiro Tsukamoto6, Yugo Mori6, Toshihiko Ueda7, Makiko Motoi8, Takanori Mori5, Shinichiro Nitta7, Masae Yamamoto8, Yuki Kishino3, Yoshiro Saito9, Ruri Hanajiri1 (1. Division of Medicinal Safety Science, National Institute of Health Sciences, 2. Mitsubishi Tanabe Pharma Corporation, 3. Daiichi Sankyo Co., Ltd., 4. Thermo Fisher Scientific Life Technologies Japan Ltd., 5. Ono Pharmaceutical Co., Ltd., 6. CMIC Pharma Science Co.,Ltd., 7. Mediford Corporation, 8. Eisai Co., Ltd., 9. National Institute of Health Sciences)

[P3-03]Generation of anti-idiotype antibodies from single rabbit B cells by Ecobody technology

*Shoji Ohuchi1, Shin Kawano1, Tomiko Yamada1, Risumi Isogai1, Tomoe Yamauchi1, Tomoya Nakanishi1 (1. iBody Inc.)

[P3-04]High-throughput Met ID analysis using UPLC x IMS system and Met ID software with site of metabolism prediction

*Tomoshige Ando1, Taiji Kawase1, Tatsuya Ezaki1 (1. Nihon Waters)

[P3-05]Determining DMPK & Changes in Plasma and Liver Lipidome Following Repeat Oral Administration of Methapyrilene Over 5 Days To Male Wistar Rats Using HRMS Targeted HILIC-MS/MS & Imaging Mass Spectrometry

*Thanai Paxton1, Robert S Plumb2, Stephen Lai2, Anthony Midey2, Ian D Wilson3 (1. Nihon Waters K.K., 2. Waters Corporation, Milford, MA, USA, 3. Imperial College, Division of Systems Medicine, Department of Metabolism Department of Metabolism)

[P3-06]Introduction of a New Aptamer Screening Method Combining High-Throughput Experiment and Deep Learning

*Yuichiro Asai1, Kosaku Noba1, Megumi Tominaga1, Rieko Takahashi1 (1. KONICA MINOLTA, INC.)

[P3-07]A Digital Platform for the Development of Next-Generation Antibody Drug Conjugates (ADCs) and Other Antigen-Targeting Conjugates

*Ryo Masuda1, Yoko Okushima1, Meripet Yamanaka1, Chong Kok Teo2, Jessy Sheng3, Sebastian Kolinko4, Andreas Kaufmann4, Christoph Freiberg4 (1. Genedata KK, Tokyo, Japan, 2. Genedata Pte LTD, Singapore, 3. Genedata Inc., San Francisco, CA, USA, 4. Genedata AG, Basel, Switzerland)

[P3-08]Ultra-fast Online Solid Phase Extraction LC/MS/MS Method for the Simultaneous Analysis of Steroid Hormones

*Daiki Fujimura1, Eishi Imoto2, Toshiya Matsubara2, Vikki Johnson2, Logan Miller2, Yusuke Osaka1 (1. Shimadzu Corporation, 2. Shimadzu Scientific Instruments)

[P3-09]Understanding proper buffer systems and assay format to overcome interference in developing immunogenicity assays to ADC’s.

*Christopher Hammond Hammond1, Zhenqiang Li1, Hema Desai1 (1. Syneos Health)

[P3-10]Application of an ultra-sensitive qPCR method to detect EGFR T790M mutation in cell lines and clinical samples

*Nan Jia1, Shenglei Yuan1, Guofu Lu1, Dan Wang1, Chenpu Zhang1, Jianbo Diao1, Wenzhong Liang1, Lan Li1 (1. Bioanalytical Services, WuXi AppTec (Shanghai) Co., Ltd.)

[P3-11]The development and qualification of bioanalytical methods for complement biomarkers

*Wenwen Sheng1, Mingming Wang1, Jinpeng Li1, Xiaoying Jin1, Lan Li2 (1. WuXi AppTec, Inc./ BAS department (Suzhou Site), 2. WuXi AppTec, Inc./ BAS department (Shanghai Site))

[P3-12]Generation and Detailed Characterization of an Affinity Purified Polyclonal Chicken IgY to Human IgG with Negligible Cross-Reactivity to Monkey IgG

Derrick Johnson1, *Hisanori Hara1, Adam S. Kinne1, Elijah S. Parmer1, Alyssa N. Cieslak1, Nicholas L. Frecker1, Sanofar J. Abdeen1, Ronald R. Bowsher1 (1. B2S Life Sciences)

[P3-13]Study of the Development of Cyclic Peptides in Biological Samples by Tandem Quadrupole Mass Spectrometer

*Kayo Iwasaki1, Suguru Fukuda1, Mitsuhiko Kawabata1, Katsunori Ieki1 (1. Shin Nippon Biomedical Laboratories, LTD)

[P3-14]Development of NonIP-RP-LC/MS for bioanalysis of oligonucleotide therapeutics

*Yoshiharu Hayashi1, Yuchen Sun2, Aki Koyama1 (1. CMIC Pharma Science Co., Ltd., 2. National Institute of Health Sciences)

[P3-15]核酸医薬品のADA測定法の構築

*Ryu Hirayama1, Nobuhiro Suzuki1, Yoshiharu Hayashi1, Miho Marumoto1, Yoji Hayase2, Kaori Harada2, Miyuki Hori2, Yumi Nishiguchi1, Aki Koyama1 (1. CMIC Pharma Science Co., Ltd., 2. TAGCyx Biotechnologies Inc.)

[P3-16]Development and validation of an analytical method to quantify coproporphyrin I, an endogenous biomarker to assess drug-drug interaction, in human plasma

*Kazusa Nozaki1, takeru yamaguchi1, takuma shigeyama1 (1. Sumika Chemical Analysis Service, Ltd./Bioanalysis Group)
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