[2T15] Cell Structure and Function / Cycle, Development 03

2:13 PM - 2:22 PM JST(5:13 AM - 5:22 AM UTC)

[2T15-08] A PI(3,5)P₂/ESCRT-III axis terminates STING signalling by facilitating TSG101-mediated lysosomal microautophagy

^○Tsumugi Shoji¹, Ayumi Shinojima¹, Satoshi Kusumi², Daisuke Koga³, Kojiro Mukai¹, Jun Nakayama⁴, Shigeki Higashiyama^4,5,6, Yoshihiko Kuchitsu¹, Tomohiko Taguchi¹ (1.Laboratory of Organelle Pathophysiology, Department of Integrative Life Sciences, Graduate School of Life Sciences, Tohoku University, Miyagi, Japan, 2.Department of Morphological Sciences, Kagoshima University, Kagoshima, Japan, 3.Department of Microscopic Anatomy and Cell Biology, Asahikawa Medical University, Hokkaido, Japan, 4.Department of Oncogenesis and Growth Regulation, Research Institute, Osaka International Cancer Institute, Osaka, Japan, 5.Department of Biochemistry and Molecular Genetics, Ehime University Graduate School of Medicine, Ehime, Japan, 6.Division of Cell growth and Tumor Regulation, Ehime University Proteo-Science Center, Ehime, Japan)

キーテクノロジー：発光レポーターアッセイ

Keywords:

リン脂質、cGAS-STING経路、リソソーム

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