The 97th Annual Meeting of the Japanese Biochemical Society
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Session Details

Symposium

[2S06m]Intramembrane proteolysis: towards understanding of the mechanism and its medical application

Thu. Nov 7, 2024 9:00 AM - 11:00 AM JST
Thu. Nov 7, 2024 12:00 AM - 2:00 AM UTC
Room6(G302)
Organizers：Yohei Hizukuri（Institute for Life and Medical Sciences, Kyoto University）, Terukazu Nogi（Graduate School of Medical Life Science, Yokohama City University）
9:00 AM - 9:06 AM JST(12:00 AM - 12:06 AM UTC)

[2S06m-00]Understanding the substrate selectivity of the bacterial intramembrane protease RseP and generation of a basis for the development of its inhibitor

○Yohei Hizukuri (Institute for Life and Medical Sciences, Kyoto University)
キーテクノロジー：in vivo生化学
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9:06 AM - 9:25 AM JST(12:06 AM - 12:25 AM UTC)

[2S06m-01]Structural analysis of bacterial site-2 protease homologs towards selective regulation of substrate cleavage activity

○Terukazu Nogi (Graduate School of Medical Life Science, Yokohama City University)
キーテクノロジー：構造生物学
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9:25 AM - 9:44 AM JST(12:25 AM - 12:44 AM UTC)

[2S06m-02]Understanding the substrate selectivity of the bacterial intramembrane protease RseP and generation of a basis for the development of its inhibitor

○Yohei Hizukuri (Institute for Life and Medical Sciences, Kyoto University)
キーテクノロジー：in vivo生化学
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9:44 AM - 10:03 AM JST(12:44 AM - 1:03 AM UTC)

[2S06m-03]Maturation of HCV core protein by Signal Peptide Peptidase

○TORU OKAMOTO (Department of Microbiology, Juntendo University School of Medicine)
キーテクノロジー：ウイルス学
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10:03 AM - 10:22 AM JST(1:03 AM - 1:22 AM UTC)

[2S06m-04]Understanding and Regulation of Proteolytic Systems in the Pathogenesis of Alzheimer Disease

○Taisuke Tomita (Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo)
キーテクノロジー：酵素活性測定
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10:22 AM - 10:41 AM JST(1:22 AM - 1:41 AM UTC)

[2S06m-05]Prediction of sequential cleavage by γ-secretase and cleavage site preferences

○Akio Fukumori (Osaka Medical and Pharmaceutical University)
キーテクノロジー：膜内切断
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10:41 AM - 11:00 AM JST(1:41 AM - 2:00 AM UTC)

[2S06m-06]Ceramide-mediated regulatory mechanism for intramembrane proteolysis of endoplasmic reticulum-resident transcription factor OASIS

○Issei Omura1, Kazunori Imaizumi2, Atsushi Saito1 (1.School of Medical Sciences,and College of Medical, Kanazawa University, 2.Department of Biochemistry, Graduate School of Biomedical and Health Sciences, Hiroshima University)
キーテクノロジー：免疫染色
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