[2T07] Biology of Diseases 05 | The 97th Annual Meeting of the Japanese Biochemical Society

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Talk

[2T07]Biology of Diseases 05

Thu. Nov 7, 2024 1:10 PM - 2:40 PM JST
Thu. Nov 7, 2024 4:10 AM - 5:40 AM UTC

Room7(G301)

Organizers: Takahiro Ito（Kyoto University）, Koichi Nishiyama（Faculty of Medicine, University of Miyazaki）

1:10 PM - 1:19 PM JST(4:10 AM - 4:19 AM UTC)

[2T07-01]Saving the Fetus from Intrauterine Hyperglycemia: Unraveling the Protective Mechanisms of Maternal Functional Lipids

^○Akio Nakamura¹, Hitomi Yoshizaki², Haruka Okami³, Saki Tsutsumi⁴, Akiyo Toriumi⁵, Eri Miyata¹, Ritsuko Kawaharada⁶ (1.Department of Molecular Nutrition, Faculty of Human Life Sciences, Jissen Women's University, 2.Department of Bioregulatory Science (Physiology), Nippon Medical School, 3.Department of Neurophysiology & Neural Repair, Graduate School of Medicine, Gunma University,, 4.Department of General Surgical Science, Graduate School of Medicine, Gunma University, 5.Department of Public Health, Graduate School of Medicine, Gunma University, 6.Department of Health and Nutrition, Takasaki University of Health and Welfare)

キーテクノロジー：機能性脂質で糖化ストレスの緩和

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1:19 PM - 1:28 PM JST(4:19 AM - 4:28 AM UTC)

[2T07-02]Prolyl isomerase Pin1 in hepatocytes exacerbates both obesity and nonalcoholic steatohepatitis which are induced by high fat high cholesterol diet.

Yuri Kido, Machi Kanna, Mikako Nakanishi, Tomoichiro Asano, ^○Yusuke Nakatsu (Department of Medical Science, Graduate School of Medicine, Hiroshima University)

キーテクノロジー：RNA-seq

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1:28 PM - 1:37 PM JST(4:28 AM - 4:37 AM UTC)

[2T07-03]LRBA is a novel risk factor for MAFLD (Metabolic dysfunction-associated fatty liver disease)

^○Daisuke Oikawa¹, Yoshinori Okina¹, Min Gi², Minh Duc Pham³, Thi Thanh Thuy Le⁴, Hiroko Ikenaga³, Tsutomu Matsubara⁵, Hirotaka Takahashi⁶, Takuro Horii⁷, Izuho Hatada⁷, Tatsuya Sawasaki⁶, Hidetaka Kosako⁸, Norifumi Kawada³, Fuminori Tokunaga¹ (1.Dept. of Med. Biochem., Grad. Sch. of Med., Osaka Metropol. Univ., 2.Dept. of Environ. Risk Aces., Grad. Sch. of Med., Osaka Metropol. Univ., 3.Dept. of Hepatol., Grad. Sch. of Med., Osaka Metropol. Univ., 4.Dept. of Glo. Educ. Med. Sci., Grad. Sch. of Med., Osaka Metropol. Univ., 5.Dept. of Anat. Regen. Biol., Grad. Sch. of Med., Osaka Metropol. Univ., 6.PROS., Ehime. Univ., 7.Lab. of Genome Sci., Inst. for Mol. Cell. Res., Gunma Univ., 8.Inst. of Adv. Med. Sci., Tokushima Univ.)

キーテクノロジー：single cell fixed RNA-seq

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1:37 PM - 1:46 PM JST(4:37 AM - 4:46 AM UTC)

[2T07-04]Investigation of the relationship between lysosomal stress responses and the onset and progression of neuromuscular diseases

^○Mai Makino^1,2, Kazuha Nagae¹, Shinko Kobashigawa¹, Takao Kiriyama³, Nobuyuki Eura³, Tomo Shiota³, Hitoki Nanaura³, Taro Mannen⁴, Kazuma Sugie^2,3, Shuhei Nakamura^1,2 (1.Department of Biochemistry, Nara Medical University, 2.Center for Autophagy and Anti-Aging Research, Nara Medical University, 3.Department of Neurology, Nara Medical University, 4.College of Life Sciences, Ritsumeikan University)

キーテクノロジー：イメージング

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1:46 PM - 1:55 PM JST(4:46 AM - 4:55 AM UTC)

[2T07-05]Upregulation of IL-1beta, IL-6, and IL-8 by intermittent hypoxia in human monocytes through downregulation of microRNA-146a

^○Shin Takasawa¹, Mai Makino¹, Ryogo Shobatake^1,2, Akiyo Yamauchi¹, Sumiyo Sakuramoto-Tsuchida¹, Tomoko Uchiyama^1,3, Maiko Takeda³, Yoshinori Takeda^1,4, Keita Mizuta¹, Keito Asai¹, Hiroyo Ota^1,5 (1.Dept. of Biochem., Nara Med. Univ., 2.Dept. of Neurol., Nara Med. Univ., 3.Dept. of Diagnostic Pathol., Nara Med. Univ., 4.Dept. of Obstet. Gynecol., Nara Med. Univ., 5.Dept. of Respir. Med., Nara Med. Univ.)

キーテクノロジー：microRNA

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1:55 PM - 2:04 PM JST(4:55 AM - 5:04 AM UTC)

[2T07-06]Identification of human STING variants responsible for the onset of COPA syndrome

^○Shogo Koide, Haruka Kemmoku, Yoshihiko Kuchitsu, Tomohiko Taguchi (Organelle Pathophysiology, Grad. Sch. of Life Sci., Tohoku Univ.)

キーテクノロジー：超解像共焦点顕微鏡

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2:04 PM - 2:13 PM JST(5:04 AM - 5:13 AM UTC)

[2T07-07]Discovery of Novel Ligands with High Affinity for Mutant Vitamin D Receptors Causing Type II Rickets

^○Yuki Okamoto¹, Hiroki Mano¹, Fumihiro Kawagoe², Masashi Takaano², Miyu Nishikawa¹, shinichi Ikushiro¹, Atsushi Kittaka², Toshiyuki Sakaki¹, Kaori Yasuda¹ (1.Toyama Prefectural University, 2.Teikyo University)

キーテクノロジー：分割型ルシフェラーゼ

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2:13 PM - 2:22 PM JST(5:13 AM - 5:22 AM UTC)

[2T07-08]Molecular mechanism underlaying increasement of aquaporin-1 expression in pulmonary fibrosis

^○Shin-ichi Muroi^1,5, Jun-Dal Kim^1,5, Tomoko Misawa², Yoshitoshi Kasuya⁴, Takuji Suzuki², Koichiro Tatsumi³, Yoshimi Nakagawa¹ (1.Institute of National Medicine, University of Toyama, 2.Department of Respirology, Graduate School of Medicine, Chiba University, 3.Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, 4.Faculty of Pharmacy, Juntendo University, 5.AMED-CREST, Japan Agency for Medical Research and Development)

キーテクノロジー：遺伝子改変マウス

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2:22 PM - 2:31 PM JST(5:22 AM - 5:31 AM UTC)

[2T07-09]Oleic acid rescues peroxisome-deficient CHO cells from very long-chain fatty acid-induced apoptosis

^○Ali Hanif¹, Mone Yamanishi¹, Sunagaw Keigo¹, Rumana Yesmin Hasi¹, Mutsumi Aihara¹, Yoshimasa Hamada², Masato Miyake², Oyadomari Seiichi², Tamotsu Tanaka¹ (1.Graduate School of Technology, Industrial and Social Sciences, Tokushima University, 2.Division of Molecular Biology, Institute for Genome Research, Institute of Advanced Medical Sciences, Tokushima University)

キーテクノロジー：GC, LC-MS/MS, Western blot

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