Session Details

[2T10]Immunity and Infection 02

Thu. Nov 7, 2024 1:10 PM - 2:40 PM JST
Thu. Nov 7, 2024 4:10 AM - 5:40 AM UTC
Room10(G315)
Organizers: Chiharu Nishiyama(Tokyo University of Science), Rikinari Hanayama(Kanazawa University)

[2T10-01]The interaction of NLRP3 and sphingosine-1-phosphate lyase is an essential priming event for inflammasome activation

Fumiyuki Sasaki, Masumi Shimizu, Misaki Wakasugi, Hinata Hirashima, Rimpei Morita (Nippon Medical School, Department of Microbiology and Immunology)
キーテクノロジー:CRISPR/Cas9システム
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[2T10-02]Endogenous regulation of NLRP3 inflammasome activation through supersulfidation

Tianli Zhang1,2, Hiroyasu Tsutsuki2, Kazuaki Monde2, Akiyuki Nishimura3, Tetsuro Matsunaga1, Motohiro Nishida3,4, Takaaki Akaike5, Tomohiro Sawa2 (1.Center for Integrated Control, Epidemiology and Molecular Pathophysiology of Infectious Diseases, Akita University, 2.Department of Microbiology, Graduate School of Medical Sciences, Kumamoto University, 3.Division of Cardiocirculatory Signaling, National Institute for Physiological Sciences, National Institutes of Natural Sciences, 4.Department of Physiology, Graduate School of Pharmaceutical Sciences, Kyushu University, 5.Department of Environmental Medicine and Molecular Toxicology, Tohoku University Graduate School of Medicine)
キーテクノロジー:ビオチンスイッチアッセイ
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[2T10-03]NRF2 Hyperactivation in the Epidermis Induces Atopic Dermatitis

Tomohiro Edamitsu1, Keiko Taguchi1, Eisaku Ogawa2, Ryuhei Okuyama2, Masayuki Yamamoto1 (1.Department of Biochemistry and Molecular Biology, Tohoku Medical Megabank Organization, Tohoku University, 2.Department of Dermatology, Shinshu University School of Medicine)
キーテクノロジー:遺伝子改変マウス
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[2T10-04]Sex differences in microglial miRNA expression and inflammatory regulation

Haolin Zheng1, Mizokami Akiko2, Sano Tomomi1, Yamawaki Yosuke4, Jimi Eijiro3, Kanematsu Takashi1 (1.Department of Cell Biology, Aging Science, and Pharmacology, Kyushu University, 2.OBT Research Center, 3.Laboratory of Molecular and Cellular Biochemistry, Faculty of Dental Science, Kyushu University, 4.Department of Advanced Pharmacology, Daiichi University of Pharmacy)
キーテクノロジー:Microarray analysis techniques
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[2T10-05]BTB and CNC homology 1 deficiency disrupts intestinal IgA secretion through regulation of polymeric immunoglobulin receptor expression

Yasuki Higashimura1, Takakazu Mitani2, Tomohisa Takagi3, Akihiko Muto4, Kazuhiko Igarashi4, Yuji Naito5 (1.Department of Food Science, Ishikawa Prefectural University, 2.Division of Food Science and Biotechnology, Graduate School of Science and Technology, Shinshu University, 3.Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 4.Department of Biochemistry, Tohoku University Graduate School of Medicine, 5.Department of Human Immunology and Nutrition Science, Kyoto Prefectural University of Medicine)
キーテクノロジー:flow cytometry
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[2T10-06]Chemogenetic G12 signal in B lymphocytes suppresses formation of germinal center

Nozomi Kamakura1, Kaito Arai1, Manae Tatsumi1, Tasuku Kawano2, Tomoko Takahashi2, Asuka Inoue1,3 (1.Graduate School of Pharmaceutical Sciences, Tohoku University, 2.Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 3.Graduate School of Pharmaceutical Sciences, Kyoto University)
キーテクノロジー:ケモジェネティクス
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[2T10-07]The potential of treatment targeting SIRPα for head and neck squamous cell carcinoma

Takashi Ueda1,2,3, Saki Matsumoto3, Tomoko Takai3, Satomi Komori3, Tania Afroj3, Yasuyuki Saito1, Takenori Kotani1, Ken-ichi Nibu2, Takashi Matozaki1,3, Yoji Murata1 (1.Division of Molecular and Cellular Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, 2.Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, 3.Division of Biosignal Regulation, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine)
キーテクノロジー:貪食実験
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[2T10-08]Innovative mRNA vaccine-based CAR-T cell therapy targeting FAP in solid tumors

Meng Sikun1, Tomoaki Hara1, Shotaro Tatekawa2, Tetsuya Sato3, Yoshiko Saito1, Yasuko Arao1, Hidetoshi Eguchi4, Kazuhiko Ogawa2, Yutaka Miura5, Hideshi Ishii1 (1.Department of Medical Data Science, Osaka University Graduate School of Medicine, 2.Department of Radiation Oncology, Osaka University Graduate School of Medicine, 3.Faculty of Medicine, Saitama Medical University, 4.Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, 5.Institute of Innovative Research, Tokyo Institute of Technology)
キーテクノロジー:mRNA-based CAR-T cell therapy
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[2T10-09]PPM1D regulates function of neutrophil-subset via splice variant of CEACAM3

Rui Kamada, Fuki Kudoh, Tatsuya Kodama, Ayane Aikawa, Kodai Iwaki, Kazuyasu Sakaguchi (Laboratory of Biological Chemistry, Department of Chemistry, Faculty of Science, Hokkaido University)
キーテクノロジー:ホスファターゼ阻害剤
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[2T10-10]Molecular Mechanisms of Diverse Chemokine Recognition and Downstream Signaling Selectivity of Chemokine Receptors

Fumiya K. Sano1, Shirsha Saha2, Saloni Sharma2, Hiroaki Akasaka1, Parishmita Sarma2, Takaaki A. Kobayashi1, Yuzuru Itoh1, Yoshiaki Kise1, Wataru Shihoya1, Arun K. Shukla2, Osamu Nureki1 (1.Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2.Department of Biological Sciences and Bioengineering Indian Institute of Technology, Kanpur)
キーテクノロジー:クライオ電子顕微鏡法
Comment()