[3S02a] A new dimension of life emerging from sulfur research | The 97th Annual Meeting of the Japanese Biochemical Society

Session Details

Symposium

[3S02a]A new dimension of life emerging from sulfur research

Fri. Nov 8, 2024 1:35 PM - 3:35 PM JST
Fri. Nov 8, 2024 4:35 AM - 6:35 AM UTC

Room2(G404)

Organizers：Hozumi Motohashi（Tohoku University Graduate School of Medicine / Institute of Development, Aging and Cancer, Tohoku University）, Takaaki Akaike（Tohoku University Graduate School of Medicine）

Sponsored by：Grant-in-Aid for Transformative Research Areas (A) Sulfur Biology

1:35 PM - 1:53 PM JST(4:35 AM - 4:53 AM UTC)

[3S02a-01]Physiological roles of CARS-dependent supersulfide production

^○Shohei Murakami¹, Ryutaro Komori¹, Seiryo Ogaka², Masanobu Morita², Takaki Akaike², Hozumi Motohashi¹ (1.Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, 2.Department of Environmental Medicine and Molecular Toxicology, Tohoku University Graduate School of Medicine)

キーテクノロジー：Flow cytometry

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1:53 PM - 2:17 PM JST(4:53 AM - 5:17 AM UTC)

[3S02a-02]Octosulfur (S8) is a reservoir for supersulfides in mammals, which enables protection against lipid peroxidation

^○Uladzimir Barayeu^1,2, Tsuyoshi Takata¹, Tetsuro Matsunaga¹, Seiryo Ogata¹, Yuka Unno¹, Mike Lange³, Minkyung Jung¹, Jun Yoshitake¹, Masanobu Morita¹, James A. Olzmann³, Hozumi Motohashi⁴, Takaaki Akaike¹ (1.Department of Environmental Medicine and Molecular Toxicology, Tohoku University Graduate School of Medicine, 2.Max Planck Institute for Polymer Research, 3.Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, 4.Department of Medical Biochemistry, Tohoku University Graduate School of Medicine)

キーテクノロジー：mass spectroscopy

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2:17 PM - 2:35 PM JST(5:17 AM - 5:35 AM UTC)

[3S02a-03]X-ray and Cryo-EM structures of the SUF system involved in de novo iron-sulfur cluster biosynthesis

^○Kei Wada^1,2, Yoshikazu Tanaka³ (1.Department of Medical Sciences, University of Miyazaki, 2.Frontier Science Research Center, University of Miyazaki, 3.Graduate School of Life Sciences, Tohoku University)

キーテクノロジー：Synchrotron radiation & cryoEM

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2:35 PM - 2:53 PM JST(5:35 AM - 5:53 AM UTC)

[3S02a-04]Exploring the pathways of sulfur modification in mitochondrial tRNAs

^○Haruna Tani¹, Raja Ahmad Raja Norazireen¹, Longteng Zhang¹, Keitaro Umezawa², Akiyuki Nishimura³, Motohiro Nishida^3,4, Shungo Adachi⁵, Yuhei Araiso⁶, Fan-Yan Wei¹ (1.Institute of Development, Aging and Cancer, Tohoku University, 2.Tokyo Metropolitan Institute for Geriatrics and Gerontology, 3.National Institute for Physiological Sciences, 4.Graduate School of Pharmaceutical Sciences, Kyushu University, 5.National Cancer Center Research Institute, 6.Graduate School of Medical Science, Kanazawa University)

キーテクノロジー：RNA modification analysis

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2:53 PM - 3:11 PM JST(5:53 AM - 6:11 AM UTC)

[3S02a-05]Supersulfide catabolism underlies cardiac vulnerability to ischemic stress

^○Akiyuki N. Nishimura¹, Xiaokang T. Tang¹, Yuri T. Kato², Tomoya I. Ito², Motohiro N. Nishida^1,2 (1.Division of Cardiocirculatory Signaling, National Institute for Physiological Sciences, 2.Department of Physiology, Graduate school of Pharmaceutical Sciences, Kyushu University)

キーテクノロジー：Supersulfide imaging

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3:11 PM - 3:35 PM JST(6:11 AM - 6:35 AM UTC)

[3S02a-06]Identification of Druggable and Redox Vulnerabilities in Cancer

^○Liron Barpeled (Massachusetts General Hospital Harvard Medical School)

キーテクノロジー：CRISPR Screen

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