[LP06] Structural biology, prediction of function and drug design | The 97th Annual Meeting of the Japanese Biochemical Society

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Poster(Late-breaking Abstracts)Proteins

[LP06]Structural biology, prediction of function and drug design

Wed. Nov 6, 2024 1:40 PM - 3:40 PM JST
Wed. Nov 6, 2024 4:40 AM - 6:40 AM UTC

Poster Room(G1-G4)

1:40 PM - 2:40 PM JST(4:40 AM - 5:40 AM UTC)

[1P-413]In silico screening for drugs to disaggregate Alzheimer's disease-type tau fibrils

^○Jia Qimin^1,2,3, Shingo Tamai^1,3, Takashi Nomura¹, Yuxin Chen^1,3, John Burke¹, Hideyuki Miyatake^1,2, Motomasa Tanaka^1,2,3 (1.RIKEN Center for Brain Science, 2.Graduate School of Science and Engineering, Saitama University, 3.Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University)

キーテクノロジー：in silicoスクリーニング

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2:40 PM - 3:40 PM JST(5:40 AM - 6:40 AM UTC)

[1P-414]Structural Analysis and Inhibitory Mechanism of the Novel Humanized Anti-CD39 Antibody BP1202

^○Uchikubo-Kamo Tomomi¹, Toshifumi Obonai², Motoya Mie², Mikako Shirouzu¹ (1.RIKEN Center for Biosystems Dynamics Research, 2.BrightPath Biotherapeutics Co., Ltd.)

キーテクノロジー：クライオ電子顕微鏡単粒子解析

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1:40 PM - 2:40 PM JST(4:40 AM - 5:40 AM UTC)

[1P-415]Chemo-mechanical Coupling Mechanism of Rotation of Human F1-ATPase by X-ray Crystallographic Studies

^○Suzuki Toshiharu^1,2,3, Eiki Yamashita⁴, Seiki Baba⁵, Kazuya Hasegawa⁵, Takashi Kumasaka⁵, Kunio Hirata⁶, Masasuke Yoshida⁷, Toru Hisabori² (1.Cluster for Pioneer Res, Riken, 2.CRL, Tokyo Inst of Tech, 3.Gen Res Inst, KHG, 4.Inst fo Protein Res, Osaka Univ, 5.JASRI, 6.SPring8 center, Riken, 7.Kyoto Sangyo Univ)

キーテクノロジー：Xray-crystallography

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2:40 PM - 3:40 PM JST(5:40 AM - 6:40 AM UTC)

[1P-416]Halogen ion-binding analysis of the ligand-binding domain of taste receptor, T1r1/T1r3 from pufferfish

^○Nagae Mana, Atsuko Yamashita (Grad. Sch. of Med., Dent. & Pharm. Sci., Okayama Univ.)

キーテクノロジー：示差走査蛍光測定法

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