Session Details
[P012]Structural biology, prediction of function and drug design
Wed. Nov 6, 2024 1:40 PM - 3:40 PM JST
Wed. Nov 6, 2024 4:40 AM - 6:40 AM UTC
Wed. Nov 6, 2024 4:40 AM - 6:40 AM UTC
Poster Room(G1-G4)
[1P-055]X-ray structure of Clostridium perfringens CppB-CppA covalent complex at the host-cell adhesion site of pili
○Yasuhiro Nonaka1, Eiji Tamai2, Hiroshi Sekiya2, Shigehiro Kamitori1,3 (1.Faculty of Medicine, Kagawa University, 2.College of Pharmaceutical Science, Matsuyama University, 3.Research Facility Center for Science & Technology, Kagawa University)
キーテクノロジー:X-ray crystal analysis
[1P-056]Attempts to inhibit the translocation of Clostridium perfringens iota toxin by cross-linking
○Noriaki Sakoda, Tomohito Yamada, Hideaki Tsuge (Fac. of life Sci., Kyoto Sangyo Univ)
キーテクノロジー:構造解析
[1P-057]Conformational dynamics in folded DNA-binding domain regulating the liquid-liquid phase separation of Hsf1
○Soichiro Kawagoe1, Hiroyuki Kumeta2, Tomohide Saio1 (1.Inst. of Adv. Med. Sci., Tokushima Univ., 2.Fac. of Adv. Life Sci., Hokkaido Univ.)
キーテクノロジー:溶液NMRによるダイナミクス解析
[1P-058]Attempt for expression of highly crystallized baculovirus polyhedrin protein and modification of its regidity
○Yuki Hada, Kanta Tsumoto (Mie University Graduate School of Engineering, Division for Applied Chemistry, Laboratory of Molecular Biotechnology)
キーテクノロジー:PCRクローニング技術
[1P-059]The unique allosteric property of crocodilian hemoglobin elucidated by cryo-EM
○Katsuya Takahashi1, Yongchan Lee1, Jay Storz2, Angela Fago3, Tomohiro Nishizawa1, Jeremy Tame1 (1.Grad. Sch. of Med. Life Sci., Yokohama City Univ., 2.Sch. of Biol. Sci., Univ. of Nebraska, 3.Dept of Bioscience, Aarhus Univ.)
キーテクノロジー:クライオ電子顕微鏡
[1P-060]Ca2+ dissociation from Pf-SCP, sarcoplasmic Ca-binding protein in Pinctada fucata, contributes to calcium transportation for shell mineralization
○Yuto Namikawa, Lingxiao Zhu, Michio Suzuki (Graduate School of Agricultural and Life Sciences, The University of Tokyo)
キーテクノロジー:multi-site calcium ion model
[1P-061]Structural analysis of a transient interaction between the first SURP domain of the SF3A1 subunit in U2 snRNP and the human splicing factor SF1 using NMR methods
○Kanako Kuwasako1, Masayuki Takizawa1, Takayuki Suzuki1, Shoko Tani1, Naohiro Kobayashi2, Taiichi Sakamoto3, Yutaka Muto1, Nobukazu Nameki4 (1.Fac. of Pharm. and Res. Inst. of Pharm. Sci., Musashino Univ., 2.RIKEN BDR, 3.Fac. of Adv. Eng., Chiba Inst., 4.Grad. Sch. of Sci. and Tech., Gunma Univ.)
キーテクノロジー:NMR
[1P-062]Cryo-EM Structure Analysis of the Amino Acid Transporter SNAT2/SLC38A2
○Haruna Inuzuka, Yongchan Lee, Tomohiro Nishizawa (Yokohama City University)
キーテクノロジー:Cryo-EM
[1P-063]Identification of the subunit that binds to the baseplate wedge of bacteriophage Mu
○Shunya Hatori, Shigeki Takeda (Graduate School of Science and Technology, Gunma University)
キーテクノロジー:自己組織化
[1P-064]The structural biological Analysis of the regulation of cellular localization through the coiled-coil region of Cytohesin1
○Yumiko Adachi1, Chihiro Minamide2, Kenshin Fujioka2, Shin-ichi Terawaki3 (1.Graduate School of Science and Engineering, Ehime university, 2.Faculty of Engineering, Ehime university, 3.Proteo-Science Center, Ehime university)
キーテクノロジー:X線結晶解析
[1P-065]Mechanistic Study on Heme Recognition and Transfer by an Iron-Acquisition Protein from Streptococcus pyogenes
○Kanta Seki, Akinobu Senoo, Saeko Yanaka, Jose M.M. Caaveiro (Kyushu University, Graduate School of Pharmaceutical Sciences)
キーテクノロジー:X-ray crystallography
[1P-066]New macromolecular crystallography endstation at NanoTerasu
○Yusuke Yamada1, Eriko Nango1,2, Masaki Yamamoto3 (1.International Center for Synchrotron Radiation Innovation Smart, Tohoku University, 2.Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 3.RIKEN SPring-8 Center)
キーテクノロジー:タンパク質結晶構造解析
[1P-067]Preparation and evaluation of epigenetic modification complex PCGF1-PRC1
○kisuke kobayashi1,3, shinsuke ito1, yuri tomabechi2, sayako kohno2, mikako shirouzu2, haruhiko koseki1,3 (1.Lab. For Developmental Genetics, RIKEN Center for Integrative Medical Sciences, 2.Lab. for Protein Functional and Structural Biology, RIKEN Center for Biosystems Dynamics Research, 3.Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University)
キーテクノロジー:クライオ電子顕微鏡
[1P-068]Examination of pH-dependent structural change in LDL receptor using high-speed atomic force microscopy and flow induced dispersion analysis
○airi Ishida1, Saki Ide1, Kenichi Umeda2,3, Aki Siozawa1, Noriyuki Kodera2, Terukazu Nogi1 (1.Yokohama City University, 2.Kanazawa University, 3.JST PRESTO)
キーテクノロジー:高速AFM, 流動誘起分散解析
[1P-069]Elucidation of the conformational change mechanism of droplet-forming protein TIA-1 using high-speed AFM
○Aya Ogino1, Holger Flechsig2, Naotaka Sekiyama3, Hiroki Konno2 (1.Graduate School of Natural Science and Technology, Kanazawa University, 2.WPI Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, 3.Graduate School of Science, Kyoto University)
キーテクノロジー:構造動態変化メカニズム
[1P-070]Analysis of the Interaction Between Cadherin Proteins CDHR5 and PCDH24 Responsible for Crohn's Disease
○Karin Fujishima, Akinobu Senoo, Saeko Yanaka, Jose M.M. Caaveiro (Kyushu University, School of Pharmaceutical Sciences)
キーテクノロジー:SEC, ITC, DSF
[1P-071]Cyclic oligoadenylate-dependent antiviral response in type III-B CRISPR-Cas effector mediated by a novel associated protein.
○Ryo Ouchi1, Yoshitomo Ito1, Shunsuke Matsumoto2, Tomoyuki Numata2 (1.Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka, Japan., 2.Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University)
キーテクノロジー:クライオ電子顕微鏡
[1P-072]Structural insights into the agonist selectivity of the adenosine A3 receptor
○Hidetaka S. Oshima1, Akiko Ogawa2, Fumiya K. Sano1, Fan-Yan Wei2, Wataru Shihoya1, Osamu Nureki1 (1.Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 2.Institute of Development, Aging and Cancer, Tohoku University)
キーテクノロジー:クライオ電子顕微鏡法
[1P-073]Structural basis for the mechanism of caffeine-induced recovery of loss-of-function RyR2 mutants.
○Yuya Otori1, Raymond Burton-Smith2, Nagomi Kurebayashi3, Kazuyoshi Murata2, Hiroaki Kato1,4, Takashi Murayama3, Haruo Ogawa1 (1.Kyoto University Graduate School of Pharmaceutical Sciences, 2.The Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, 3.Juntendo University Graduate School of Medicine, 4.RIKEN SPring-8 Center)
キーテクノロジー:クライオ電子顕微鏡
[1P-074]Investigation of stabilizers to stabilize of human serum albumin domain I-fused human lactoferrin
○Aran Maeda, Shiori Suzuki, Masahiro Kimura, Atsushi Sato (Graduate School of Bionics, Computer and Media Sciences, Bionics Program, Tokyo University of Technology)
キーテクノロジー:結合アッセイ
[1P-075]Measurements of inorganic phosphate at high concentrations using low-affinity mutants of the phosphate-binding protein
○Shota Shimada1, Nobukiyo Tanaka2, Tomoko Masaike2 (1.Grad. Sch. of Sci. and Tech., Tokyo Univ. of Sci., 2.Dept. Appl. Biol. Sci., Tokyo Univ. of Sci.)
キーテクノロジー:蛍光強度変化によるリン酸検出
[1P-076]Structural insights into the enhancement of RyR2 activity by mutant calmodulin
○Ayuna Tsutsumi1, Yuya Otori1, Raymond Burton-Smith2, Nagomi Kurebayashi3, Kazuyoshi Murata2, Hiroaki Kato1,4, Takashi Murayama3, Haruo Ogawa1 (1.Kyoto University Graduate School of Pharmaceutical Sciences, 2.The Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, 3.Juntendo University Graduate School of Medicine, 4.RIKEN SPring-8 Center)
キーテクノロジー:クライオ電子顕微鏡