Session Details
[P015]Proteolysis
Wed. Nov 6, 2024 1:40 PM - 3:40 PM JST
Wed. Nov 6, 2024 4:40 AM - 6:40 AM UTC
Wed. Nov 6, 2024 4:40 AM - 6:40 AM UTC
Poster Room(G1-G4)
[1P-093]Function of the HECT E3 ligases UBE3C and HERC3 on the ER-associated degradation of CFTR.
○Yuka Kamada1, Hazuki Tateishi1, Uta Nakayamada1, Saori Katoh1, Hirotaka Takahashi2, Tsukasa Okiyoneda1 (1.Dept. of Biomed. Sci., Sch. of Biol. and Env. Sci., Kwansei Gakuin Univ., 2.Proteo-Science Center, Ehime Univ.)
キーテクノロジー:HiBiT ERAD assay
[1P-094]Development of a protein system that selectively unfolds and degrades target protein aggregates
○Momoka Tamura1, Masashi Miki1, Ayari Tatsumi1, Yo-hei Watanabe1,2 (1.Department of Biology, Graduate School of Natural Science, Konan University, 2.Institute for Integrative Neurobiology, Konan University)
キーテクノロジー:融合タンパク質
[1P-095]Calpain7 involves in negative regulation of myoblast differentiation
○Atsushi Irie, Yasuko Ono (Tokyo Metropolitan Institute of Medical Science, Calpain Project)
キーテクノロジー:定量的PCR
[1P-096]Genetic screen for factors regulating lysosomal degradation of aberrant membrane proteins
○Yuki Hayashi1,2, Kento Hagiya1, Noboru Mizushima2, Hidenori Ichijo1,3 (1.Laboratory of Cell Signaling, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 2.Department of Biochemistry and Molecular Biology, Graduate School of Medicine, The University of Tokyo, 3.Cell Signaling and Stress Responses Laboratory, TMDU Advanced Research Institute, Tokyo Medical and Dental University)
キーテクノロジー:CRISPRスクリーニング
[1P-097]Identification of cellular pathways regulating targeted protein degradation
○Yuki Mori1,2, Yoshino Akizuki1,2, Rikuto Honda1,2, Fumiaki Ohtake1,2 (1.Institute for Advanced Life Science, Hoshi University, 2.Graduate school of Pharmaceutical Science, Hoshi University)
キーテクノロジー:標的タンパク質分解
[1P-098]Elucidating the mechanism of p53 metabolism through the nuclear Ubiquitin Fusion Degradation pathway
○Rintaro Sumikama1, Takahiro Yanagawa1, Shoshiro Hirayama1, anri Nishizawa1, Hidetaka Kosako2, Shigeo Murata1 (1.Laboratory of Protein Metabolism, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 2.Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University)
キーテクノロジー:CRISPR KO screen, TMT-MS/MS
[1P-099]TEB4, HRD1 and RNF145 safeguards mistargeted OXPHOS-MIM proteins in the ER
○Yuichi Tsuchiya1, Nikita Sergejevs2, Mike Renne2,3, Michael van de Weijer2, Pedro Carvalho2 (1.CBS, RIKEN, 2.Sir William Dunn School of Pathology, The University of Oxford, 3.Saarland Uversity)
キーテクノロジー:CRISPR genome-wide screen
[1P-100]Analysis of Clusterin Endocytosis Pathway by Identification of Receptor HSPGs
○Kamikawa Kanna1, Akira Matsuura2, Eisuke Itakura2 (1.Department of Biology, Graduate school of Science and Engineering, Chiba University, 2.Department of Biology, Graduate school of Science, Chiba University)
キーテクノロジー:蛍光タンパク質