[P093] Carbohydrate-related enzymes

3:45 PM - 4:30 PM JST(6:45 AM - 7:30 AM UTC)

[2P-024] Search for specific small molecule compounds that regulate the enzymatic activity of protein O-glucosyltransferase 1, POGLUT1, towards controlling the Notch signaling pathway

^○Misaki Nagaya¹, Yuuki Kurebayashi¹, Riyo Imamura², Katsuki Sato¹, Yuto Yamada¹, Megumi Takeuchi¹, Yohei Tsukamoto¹, Akira Minami^1,3, Tadanobu Takahashi¹, Takayoshi Okabe², Hirotatsu Kojima², Tetsuya Okajima ^4,5, Hideyuki Takeuchi¹ (1.Sch. Pharm. Sci., Univ. of Shizuoka, 2.DDI, Grad. Sch. Pharm. Sci., Univ. of Tokyo , 3.Fac. Pharm., Juntendo Univ., 4.Grad. Sch. Med., Nagoya Univ., 5.iGCORE, Nagoya Univ.)

キーテクノロジー：糖転移酵素活性制御剤

Keywords:

糖転移酵素,Notchシグナル,O-グルコース糖鎖,POGLUT1,低分子化合物ライブラリー

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