[2S16m] Expanding the roles of molecular chaperones beyond conventional paradigms

9:59 AM - 10:22 AM JST(12:59 AM - 1:22 AM UTC)

[2S16m-04] "ERAD body" as a platform facilitating the degradation of misfolded proteins

^○Ami Sugisawa¹, Shiori Ueda^1,2, Yuika Okuda¹, Yasuko Fukuda¹, Kohei Yokosawa³, Keisuke Mochida^4,5, Shinya Tahara³, Motomasa Tanaka⁶, Takakazu Nakabayashi³, Kazuhiro Nagata^1,6,7,8, Ryo Ushioda^1,6,7 (1.Graduate School of Life Sciences, Division of Life Sciences, Kyoto Sangyo University, 2.Division of Life Sciences, Kyoto University., 3.Graduate School of Pharmaceutical Sciences, Tohoku University., 4.Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo., 5.Laboratory for Protein Conformation Diseases, RIKEN Center for Brain Science, 6.Institute for Protein Dynamics, Kyoto Sangyo University, 7.Core Research for Evolutional Science and Technology, 8.JT Biohistory Research Hall)

キーテクノロジー：Microscopic observation

Keywords:

ER,ERAD,Phase separation,Protein quality control,Chaperone

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