Presentation Information

[3T14-03]Gasdermin-independent release of IL-1 family cytokines during apoptosis causes skin inflammation

Masahiro Nagata1,2,4, Laurens Wachsmuth1,2, Eunjin Ju1,2, Yasmin C. Schäfer1,2, Remzi O. Eren1,2, Manolis Pasparakis1,2,3 (1.Institute for Genetics, University of Cologne, 2.Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 3.Center for Molecular Medicine (CMMC), University of Cologne, Cologne, Germany, 4.Department of Medical Chemistry, Medical Research Laboratory, Institute of Integrated Research, Institute of Science Tokyo)
キーテクノロジー:Knockout of family proteins

Keywords:

IL-1 family,Caspase-8 dependent cell death,Gasdermin

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