The 98th Annual Meeting of the Japanese Biochemical Society
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Session Details

Symposium

[2S06m]Protein degradation mechanisms driving proteome remodeling

Tue. Nov 4, 2025 8:45 AM - 10:45 AM JST
Tue. Nov 4, 2025 11:45 PM - 1:45 AM UTC
Room6(Room E)
Organizers：Shigeo Murata（Graduate School of Pharmaceutical Sciences, The University of Tokyo）, Fuminori Tokunaga（Graduate School of Medicine, Osaka Metropolitan University）
8:45 AM - 9:05 AM JST(11:45 PM - 12:05 AM UTC)

[2S06m-01]Mechanisms Regulating Proteasome Function and Cellular Responses to Proteasomal Stress

○Shigeo Murata (Graduate School of Pharmaceutical Sciences, the University of Tokyo)
キーテクノロジー：mass spectrometry
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9:05 AM - 9:30 AM JST(12:05 AM - 12:30 AM UTC)

[2S06m-02]Global remodeling of the proteome in terminal differentiation

○Daniel Finley1, Ismael Boussaid2, Mark Fleming3, Starr Jiang1, Allon Klein1, Joel Mackay4, Daniel Maeso5, Karishma Patel4, Miguel Prado5, Paul Schmidt3, Brenda Schulman6, Sara Sepic6, Dawa Sherpa6, Mitchell Weiss7, Qiu Wu1 (1.Harvard Medical School, 2.Universite Paris Cite, Institut Chochin, 3.Boston Children's Hospital, 4.Univ. of Sydney, 5.ISPA, 6.Max Planck Institute of Biochemistry, 7.St Jude Children's Research Hospital)
キーテクノロジー：quantitative global proteomics
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9:30 AM - 9:50 AM JST(12:30 AM - 12:50 AM UTC)

[2S06m-03]Molecular mechanisms of hyperosmotic stress response mediated by proteasomal degradation

○Yasushi Saeki, Kouta Nakadai, Takuya Tomita (The Institute of Medical Science, The University of Tokyo)
キーテクノロジー：LC-MS/MS
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9:50 AM - 10:15 AM JST(12:50 AM - 1:15 AM UTC)

[2S06m-04]Proteasome Sequestration and Remodeling for Stress Adaptation and Their Pathological Implications

○Min J. Lee (Department of Biochemistry, Seoul National University College of Medicine)
キーテクノロジー：Proteasome homeostasis
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10:15 AM - 10:40 AM JST(1:15 AM - 1:40 AM UTC)

[2S06m-05]Structural Insights into a Bag1-Mediated Unfolded Protein Degradation by the 26S Proteasome

○Eri Sakata (Institute for Auditory Neuroscience, University Medical Center Goettingen)
キーテクノロジー：Cryo-EM
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10:40 AM - 10:45 AM JST(1:40 AM - 1:45 AM UTC)

[2S06m-06]Discussion

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