[2S12a] Protein cross-linking enzyme, transglutaminase, with multiple biological events | The 98th Annual Meeting of the Japanese Biochemical Society

The 98th Annual Meeting of the Japanese Biochemical Society

Session Details

Symposium

[2S12a]Protein cross-linking enzyme, transglutaminase, with multiple biological events

Tue. Nov 4, 2025 1:00 PM - 3:00 PM JST
Tue. Nov 4, 2025 4:00 AM - 6:00 AM UTC

Room12(Room H)

Organizers：Kiyotaka Hitomi（Graduate School of Pharmaceutical Sciences, Nagoya University）, Masayoshi Souri（Department of Public Health and Hygiene, Yamagata University Graduate School of Medical Science / Department of Molecular Patho-Biochemistry and Patho-Biology, Yamagata University School of Medicine）

1:00 PM - 1:05 PM JST(4:00 AM - 4:05 AM UTC)

[2S12a-00]Introduction

^○Kiyotaka Hitomi (Graduate School of Pharmaceutical Sciences, Nagoya University)

Comment()

1:05 PM - 1:22 PM JST(4:05 AM - 4:22 AM UTC)

[2S12a-01]Molecular mechanism and phenotypic analysis of mouse death caused by deletion of protein cross-linking enzyme TG1

^○Hideki Tatsukawa, Atsuki Takahashi, Kiyotaka Hitomi (Graduate School of Pharmaceutical Sciences, Nagoya University)

キーテクノロジー：Conditional knockout mouse

Comment()

1:22 PM - 1:39 PM JST(4:22 AM - 4:39 AM UTC)

[2S12a-02]Histological and Transcriptomic Insights into Final Differentiation as Manifested by Keratinization : Roles of Transglutaminases and Their Substrates in the Oral Epithelium

^○Katsumitsu Shimada¹, Rita Rany Roy², Satoshi Murakami¹, Hiromasa Hasegawa³ (1.Department of Clinical Pathophysiology, School of Dentistry, Matsumoto Dental University, 2.Department of Physiology, School of Dentistry, Matsumoto Dental University, 3.Department of Oral Pathology/Forensic Odontology, School of Dentistry, Aichi Gakuin University)

キーテクノロジー：Histopathology

Comment()

1:39 PM - 1:56 PM JST(4:39 AM - 4:56 AM UTC)

[2S12a-03]Regulation of Transglutaminase 2 during the acute phase of optic nerve injury in zebrafish

^○Kayo Sugitani (Div Health Sci, Grad Sch Med Sci, Kanazawa Univ.)

キーテクノロジー：TG2 Knockdown Assay

Comment()

1:56 PM - 2:26 PM JST(4:56 AM - 5:26 AM UTC)

[2S12a-04]Transglutaminase 2 promotes EMT in ovarian cancer cells by inactivating GSK3β

Ho Lee^1,2, Joon Hee Kang^1,2, ^○Soo-Youl Kim¹ (1.Division of Cancer Biology, National Cancer Center, 2.Graduate School of Cancer Science and Policy, National Cancer Center)

キーテクノロジー：gene knockdown

Comment()

2:26 PM - 2:43 PM JST(5:26 AM - 5:43 AM UTC)

[2S12a-05]Role of TG2-mediated proteostasis in liver inflammation

^○Xian-Yang Qin (RIKEN Center for Integrative Medical Sciences)

キーテクノロジー：proteome analysis

Comment()

2:43 PM - 3:00 PM JST(5:43 AM - 6:00 AM UTC)

[2S12a-06]Possible role of cellular coagulation factor XIII, a plasma transglutaminase

^○Masayoshi Souri^1,3, tsukasa Osaki^2,3, Akitada Ichinose³ (1.Department of Public Health and Hygiene, Yamagata University Graduate School of Medical Science, 2.Department of Biochemistry and Molecular Biology, Yamagata University Graduate School of Medical Science, 3.Department of Molecular Patho-Biochemistry and Patho-Biology, Yamagata University School of Medicine)

キーテクノロジー：gene targeting

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