The 98th Annual Meeting of the Japanese Biochemical Society
Advanced Search

Session Details

Symposium

[2S14e]Apolipoprotein E: A next therapeutic target for Alzheimer’s disease

Tue. Nov 4, 2025 4:30 PM - 6:30 PM JST
Tue. Nov 4, 2025 7:30 AM - 9:30 AM UTC
Room14(Room J)
Organizers：Koichi Iijima（National Center for Geriatrics and Gerontology）, Tadafumi Hashimoto（Department of Degenerative Neurological Diseases, National Center of Neurology and Psychiatry）
4:30 PM - 4:35 PM JST(7:30 AM - 7:35 AM UTC)

[2S14e-00]Introduction

○Koichi M. Iijima (National Center for Geriatrics and Gerontology)
キーテクノロジー：遺伝学
Comment()
4:35 PM - 4:58 PM JST(7:35 AM - 7:58 AM UTC)

[2S14e-01]APOE Revisited: Insights from Common and Rare Missense Variants

○Akinori Miyashita, Ai Obinata, Norikazu Hara, Tamao Tsukie, Mai Hasegawa, Masataka Kikuchi, Takeshi Ikeuchi (Department of Molecular Genetics, Brain Research Institute, Niigata University)
キーテクノロジー：ゲノムバリアント解析
Comment()
4:58 PM - 5:21 PM JST(7:58 AM - 8:21 AM UTC)

[2S14e-02]Isoform-specific effects of apolipoprotein E on Aβ deposition and implications for Alzheimer's disease therapy

○Tadafumi Hashimoto (Department of Degenerative Neurological Diseases, National Center of Neurology and Psychiatry)
キーテクノロジー：in vivo seeding 実験
Comment()
5:21 PM - 5:44 PM JST(8:21 AM - 8:44 AM UTC)

[2S14e-03]From APOE4 to APOE3: Development of an APOE-Switching Model Using the FLEx System

○Yu Yamazaki, Nayuta Nakazawa, Ruoyi Ishikawa (Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical and Health Sciences)
キーテクノロジー：“Flip-excision” switch
Comment()
5:44 PM - 6:07 PM JST(8:44 AM - 9:07 AM UTC)

[2S14e-04]The frontiers of APOE research using human stem cell models

○Hirotaka Watanabe1,2, Rei Murakami3, Hideyuki Okano1,2 (1.Division of CNS Regeneration and Drug Discovery, International Center for Brain Sciences, Fujita Health University, 2.Keio University Regenerative Medicine Research Center, 3.Keio University School of Medicine)
キーテクノロジー：iPS細胞
Comment()
6:07 PM - 6:30 PM JST(9:07 AM - 9:30 AM UTC)

[2S14e-05]Advances in Alzheimer's disease therapeutics targeting APOE

○Hiroki Sasaguri (RIKEN Center for Brain Science)
キーテクノロジー：ゲノム編集技術
Comment()
Back to Category List