Session Details

[3S10a]Gene Regulation and Phase Separation: a new horizon of biochemistry approaching mesoscale structure-function relationships

Wed. Nov 5, 2025 1:00 PM - 3:00 PM JST
Wed. Nov 5, 2025 4:00 AM - 6:00 AM UTC
Room10(Room F)
Organizers:Hiroshi Suzuki(Graduate School of Medicine, Nagoya University), Takayuki Nojima(Medical Institute of Bioregulation, Kyushu University)
共催:AMEDゲノム創薬基盤推進研究事業

[3S10a-00]Introduction

Hiroshi Suzuki (Graduate School of Medicine, Nagoya University)
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[3S10a-01]Physics of Cancer-Related Phase Separation:Probing Condensate Formation and Function using Optogenetics

Shunsuke Shimobayashi (Center for iPS Cell Research and Application, Kyoto University)
キーテクノロジー:超解像イメージング
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[3S10a-02]Molecular mechanisms linking higher-order genome organization with DNA replication timing

JAFAR SHARIF, HARUHIKO KOSEKI (RIKEN IMS)
キーテクノロジー:3次元ゲノム解析
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[3S10a-03]Phase Transition in the Nucleolus - Mechanisms, Functional Alterations, and Disease Implications

Takaaki Yasuhara (Graduate School of Biostudies, Kyoto University)
キーテクノロジー:染色体解析
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[3S10a-04]Spatial regulation of ribosomal RNA transcription by phase separation and transition

Satoru Ide1, Yasuto Murayama2, Hiroshi Kimura1, Kazuhiro Maeshima2 (1.Cell Biology Center, Institute of Integrated Research, Institute of Science Tokyo, 2.Department of Chromosome Science, National Institute of Genetics)
キーテクノロジー:凝縮体内でのIn vitro転写反応
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[3S10a-05]Long noncoding RNAs produced by dysregulated transcription termination

Takayuki Nojima (MiB, Kyushu University)
キーテクノロジー:新生RNA解析
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[3S10a-06]Transcriptional Condensates Fluidity Choreographs Coordinated Transcription of Cell Identity Genes

Koichi Ogami1, Ming M. Zheng2, Hiroshi I. Suzuki1 (1.Nagoya University Graduate School of Medicine, 2.Broad Institute of MIT and Harvard)
キーテクノロジー:一細胞一分子解析
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[3S10a-07]Closing Remarks

Takayuki Nojima (MiB, Kyushu University)
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