The 98th Annual Meeting of the Japanese Biochemical Society
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Session Details

PosterProteins

[P016]Proteolysis

Mon. Nov 3, 2025 11:00 AM - 12:30 PM JST
Mon. Nov 3, 2025 2:00 AM - 3:30 AM UTC
Poster Room(Event Hall)
11:00 AM - 11:45 AM JST(2:00 AM - 2:45 AM UTC)

[1P-094]Identification of transmembrane degrons facilitating ER-associated degradation of CFTR

○Saori Kato, Yuka Kamada, Tsukasa Okiyoneda (Dept Biomed Sci Kwansei Gakuin Univ)
キーテクノロジー：HiBiT degradation assay
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11:45 AM - 12:30 PM JST(2:45 AM - 3:30 AM UTC)

[1P-095]Development of Novel CRBN modulator for targeted protein degradation

○Keisuke Konishi1, Tatsuya Sawasaki2, Satoshi Yamanaka1,2 (1.Division of Proteo-Interactome, Section of Advanced Complex Biological Sciences, Proteo-Science Center, Ehime Univ., 2.Division of Cell-Free Sciences, Section of Fundamental Technology Development, Proteo-Science Center, Ehime Univ.)
キーテクノロジー：CRBN標的分解誘導薬
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11:00 AM - 11:45 AM JST(2:00 AM - 2:45 AM UTC)

[1P-096]Unveiling the mechanism of FAF1, FAF2, and UBXD7-mediated enhancement of VCP/p97 unfolding activity through structural prediction

○Shunki Miyauchi1, Nanako Yasumoto2, Tomoya Hino3,4, Shingo Nagano3,4, Yusuke Sato3,4 (1.Grad.Sch.Sus.Sci., Tottori Univ., 2.Fac. of Eng., Tottori Univ., 3.Grad. Sch. Eng., Tottori Univ., 4.GSC Center, Tottori Univ.)
キーテクノロジー：アンフォールディングアッセイ
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11:45 AM - 12:30 PM JST(2:45 AM - 3:30 AM UTC)

[1P-097]Identification and functional analysis of CRED2, a novel candidate extracellular chaperone that contributes to the degradation of extracellular αSyn.

○Shumpei Kamano1, Momoka Chiba1, Akira Matsuura2, Eisuke Itakura2 (1.Department of Biology, Graduate school of Science and Engineering, Chiba University , 2.Department of Biology, Graduate school of Science, Chiba University)
キーテクノロジー：細胞取り込みアッセイ
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11:00 AM - 11:45 AM JST(2:00 AM - 2:45 AM UTC)

[1P-098]Calpain-3 function in remodeling of skeletal muscle.

○Fumiko Shinkai-Ouchi1, Mayumi Shindo2, Chihiro Hisatsune1, Shoji Hata1, Yasuko Ono1 (1.Calpain group, Tokyo Metropolitan Institute of Medical Science, 2.Protein Analysis, Tokyo Metropolitan Institute of Medical Science)
キーテクノロジー：プロテオーム解析
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11:45 AM - 12:30 PM JST(2:45 AM - 3:30 AM UTC)

[1P-099]Functional analysis of extracellular uptake-type degradation transport protein KKZ

○Sayana Bun1, Akira Matsuura2, Eisuke Itakura2 (1.Department of Biology, Graduate school of Science and Engineering, Chiba University, 2.Department of Biology, Graduate school of Science, Chiba University)
キーテクノロジー：フローサイトメーター
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11:00 AM - 11:45 AM JST(2:00 AM - 2:45 AM UTC)

[1P-100]Functional analysis of DUB improving cell surface expression of CFTR mutant

○Mana Murakami, Yuto Kobayashi, Kamada Yuka, Tsukasa Okiyoneda (Dept Biomed Sci Kwansei Gakuin Univ)
キーテクノロジー：HiBiT assay, HRP assay
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11:45 AM - 12:30 PM JST(2:45 AM - 3:30 AM UTC)

[1P-101]Generation of BioID2 knock-in mice for identifying physiological substrates of ubiquitin ligase RNF183

○Miku Tanaka1, Rikuo Koyanagi1, Koji Matsuhisa1, Shinya Sato1, Takumi Okamoto2, Kazunori Imaizumi3,4, Masayuki Kaneko1 (1.Department of Pharmacology and Therapeutic Innovation, Nagasaki University Graduate School of Biomedical Sciences, 2.Center for Autophagy and Anti-Aging Research, Nara Medical University, 3.The Osaka medical research foundation for intractable diseases, 4.Department of Child Development and Molecular Brain Science, United Graduate School of Child Development, Osaka University)
キーテクノロジー：近位ビオチン標識法
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11:00 AM - 11:45 AM JST(2:00 AM - 2:45 AM UTC)

[1P-102]The snake venom metalloprotease MP09 specifically cleaves fibronectin and promotes sarcoma cell migration.

○Yongchol Shin1,2, Hirotaka Yoshie2, Takaya Nakajima2, Yuna Saitoh2, Takeshi Tohyama2, Toshihiro Suzuki3, Daisuke Okuzaki4, Yasutada Imamura2 (1.Kogakuin University, Department of Chemistry and Life Science, 2.Kogakuin University, Graduate School of Engineering, 3.Meiji Pharmaceutical University, Precision Oncology Lab., 4.Osaka University immunology frontier Research Center, Human Immunology Lab.)
キーテクノロジー：カラムクロマトグラフィー
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11:45 AM - 12:30 PM JST(2:45 AM - 3:30 AM UTC)

[1P-103]Analysis of VCP Response to Substrates Modified with branched ubiquitin chains or with both SUMO and ubiquitin chains

○Ami Hirano1, Tomoya Hino1,2,3, Shingo Nagano1,2,3, Yusuke Sato1,2,3 (1.Grad. Sch. Sus. Sci., Tottori Univ., 2.Dept. of Chem. Biol., Grad. Sch. of Eng., Tottori Univ., 3.Cent. for Res. on GSC., Tottori Univ.)
キーテクノロジー：アンフォールディング活性測定
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