[G] Fundamentals of Biomaterials and Bio-responses

10:40 AM - 10:55 AM JST(1:40 AM - 1:55 AM UTC)

[314] Fabrication of a Blood–Brain Barrier Model Using a Decellularized Brain Extracellular Matrix

○Masaya Yamamoto¹, Yuji Zhao¹, Naoto Washihira¹, Sho Fujii², Tadao Tanabe³, Tsuyoshi Kimura⁴, Mako Kobayashi¹ (1. Tohoku Univ, 2. Yamagata Univ, 3. Shibaura Inst Technol, 4. Toyo Univ)

Keywords:

Decellularized Extracellular Matrix,Blood Brain Barrier,Nanoplastics,Barrier Function

In this study, we developed an in vitro BBB model using a culture substrate composed of decellularized extracellular matrix and collagen to enhance BBB function. Furthermore, we investigated the applicability of the optimized model for evaluating the effects of environmentally aged nanoplastics.