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Mon. Mar 16, 2026

Tue. Mar 17, 2026

Wed. Mar 18, 2026

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Mitochondrial protein C15ORF48 confers resistance to DNA-damaging anticancer agents.

When inflammation and immune responses deviate from their inherent defensive functions, they undergo plastic changes that underlie diverse pathological states such as cancer, neurodegeneration, and infectious diseases. This dynamic responsiveness contributes to homeostasis at times, while promoting disease at others. We focus on the interplay between the breakdown of immune response and inflammatory stress control at the molecular level (micro) and resistance to drug therapy alongside systemic disease-modifying factors (macro). Through cutting-edge research in the nervous system, muscle tissue, and hematopoietic system, we will multifacetedly examine how the plasticity of inflammation and immunity influences biological functions and disease susceptibility, envisioning novel intervention strategies.

The 99th Annual Meeting of the Japanese Pharmacological Society

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[1-S-24]Mitochondrial protein C15ORF48 confers resistance to DNA-damaging anticancer agents.

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