The 99th Annual Meeting of the Japanese Pharmacological Society

Chair:Hiroyuki Takano(Chiba University Graduate School of Pharmaceutical Sciences), Hiromi Sato(Chiba University)

When inflammation and immune responses deviate from their inherent defensive functions, they undergo plastic changes that underlie diverse pathological states such as cancer, neurodegeneration, and infectious diseases. This dynamic responsiveness contributes to homeostasis at times, while promoting disease at others. We focus on the interplay between the breakdown of immune response and inflammatory stress control at the molecular level (micro) and resistance to drug therapy alongside systemic disease-modifying factors (macro). Through cutting-edge research in the nervous system, muscle tissue, and hematopoietic system, we will multifacetedly examine how the plasticity of inflammation and immunity influences biological functions and disease susceptibility, envisioning novel intervention strategies.