The 99th Annual Meeting of the Japanese Pharmacological Society

Chair:Yuhei Nishimura(Mie University Graduate School of Medicine), Norihito Shintani(Wakayama Medical University)

Cilia are essential protrusive organelles, each with a microtubule skeleton extending from the basal body, and are broadly classified into primary cilia and motile cilia. Primary cilia are singular structures in a cell and regulate cell proliferation and differentiation. Motile cilia exist in multiple numbers within a cell and coordinate their movement to control the transport of substances around the cell. Disruption of these ciliary functions has been increasingly implicated in the pathogenesis of various diseases, including cancer, obesity, visual and auditory impairments, and visceral heterotaxy. Consequently, cilia are gaining attention as novel therapeutic targets. This symposium aims to deepen discussions on new developments in ciliary signaling research through presentations by four researchers pursuing innovative approaches to elucidate ciliary signaling pathways. We encourage all attendees to participate actively, ask questions, and engage in discussion to help advance this exciting field.