Session Details
[1-S]Clarification of pathological mechanisms on novel functions of Na+/Ca2+ exchanger
Mon. Mar 16, 2026 8:30 AM - 10:00 AM JST
Mon. Mar 16, 2026 11:30 PM - 1:00 AM UTC
Mon. Mar 16, 2026 11:30 PM - 1:00 AM UTC
Room 3(B200)
Chair:Satomi Kita(Tokushima Bunri University Faculty of Pharmaceutical Sciences), Shigeki Moriguchi(Graduate School of Pharmaceutical Sciences, Tohoku University)
Mechanism of calcium homeostasis responds appropriately to various external stimuli and plays a key role in maintaining a stable state in the body. Na+/Ca2+ exchanger (NCX) involved is an antiporter protein (3Na+:1Ca2+) localized primarily in the plasma membrane and inner mitochondrial membrane of the cardiovascular system, nervous system and renal tubules. Disruption of calcium homeostasis regulated by NCX cause to various diseases. This symposium will feature three speakers conducting cutting-edge research focusing on the novel physiological functions of NCX, and will provide a comprehensive understanding of the pathogenesis of NCX in various organs. In this symposium, we hope that it will provide valuable insights for future research by many attendees.
[1-S-05]NCLX inhibition as a therapeutic strategy for treatment of pulmonary arterial hypertension
*Satomi Kita1,2 (1. Dept. Pharmacol., Facul. Pharmaceut. Sci., Tokushima Bunri Univ. , 2. Dept. Pharmacol., Facul. Med., Fukuoka Univ.)
[1-S-06]Modulation of calcium homeostasis via NCX in central nervous system
*Shigeki Moriguchi1 (1. Graduate School of Pharmaceutical Sciences, Tohoku University)
[1-S-07]Regulation mechanism of Na+/Ca2+ exchanger type-1 (NCX1) in renal distal tubules
*Takahiro Iwamoto1 (1. Fukuoka University Fuculty of Medicine)