Session Details

[1-S]Pathophysiology and treatment of nociplastic pain: recent advances in clinical and basic research

Mon. Mar 16, 2026 3:50 PM - 5:20 PM JST
Mon. Mar 16, 2026 6:50 AM - 8:20 AM UTC
Room 2(A200)
Chair:Atsufumi Kawabata(Kindai University), Takako Matsubara(Kobe Gakuin University)
The term -nociplastic pain- proposed by the International Association for the Study of Pain in 2017 as the third category of chronic pain distinct from nociceptive and neuropathic pain, was officially translated into Japanese in 2021. This category includes conditions such as fibromyalgia, complex regional pain syndrome, and irritable bowel syndrome, which are characterized by complex neuroplastic mechanisms involving central sensitization. The persistence and multidimensional nature of nociplastic pain are influenced by the interaction of genetic, physiological, and psychosocial factors. This symposium will present recent advances in clinical, basic, and translational research on nociplastic pain, in order to promote cross-disciplinary understanding of its pathophysiology and to discuss future directions for the development of effective treatment strategies

[1-S-58]Nociplastic pain: bridging basic and clinical research for the future of pain management

*Takako Matsubara1,2 (1. Kobe Gakuin University, 2. Aichi Medical University)
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[1-S-59]Immunological and brain volume abnormalities in patients with fibromyalgia involving nociplastic pain

*Masako Hosoi1,2, Koji Fujimoto1,2, Satoshi Izuno3, Kozo Anno1,2, Kazufumi Yoshihara4, Nobuyuki Sudo1,2,5 (1. Dept of Psychosomatic Medicine, Kyushu University Hospital, 2. Multodisciplinary Pain Center, Kyushu University Hospital, 3. Dept of Psychosomatic Medicine, Fukuoka Hospital, 4. Center for Health Sciences and Counseling, Kyushu University, 5. Dept of Psychosomatic Medicine, Graduate School of Medicine, Kyusyu University)
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[1-S-60]Plastic modulation of central pain circuits involving reward and stress systems in nociplastic pain

*Yusuke Hamada1,2, Naoko Kuzumaki1,2, Michiko Narita2, Yukiaki Suda1,2, Masako Hosoi3, Takahiro Kato4, Minoru Narita1,2 (1. Dept. Pharmacol., Hoshi univ., 2. Lab. Cancer Pathophysiol., Natl. Cancer Ctr. Res. Inst., 3. Dept. Psychosom. Med., Kyushu Univ. Hosp., 4. Dept. of Psychiatry, Hokkaido Univ. Grad. Sch. Med.)
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[1-S-61]Nociplastic pain and HMGB1, a nuclear protein

*Atsufumi Kawabata1 (1. Kindai University)
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