[20p-A601-1~16] 3.1 Basic optics and frontier of optics (merged with formerly 3.2 Equipment optics and materials)

1:45 PM - 2:00 PM JST(4:45 AM - 5:00 AM UTC)

[20p-A601-4] Formation of ultralong liposome tubes by laser-induced microbubble

〇Akemi Noguchi¹, Ken-ichi Yuyama¹, Chie Hosokawa¹, Yasushi Tanimoto¹, Yasuyuki Tsuboi¹ (1.Osaka Metropolitan Univ.)

Keywords:

Optical Tweezers,Laser Manipulation,Membrane Fusion

The applied technology of microbubbles in liquids is currently attracting a great deal of attention. In this study, we focused on a soft material used as the simplest cellular model: liposomes. We irradiated a near-infrared laser beam(λ = 808 nm) onto a gold flat film in aqueous solutions of liposome (diameter ~ 200 nm). A microbubble was generated at the focal point on the plasmon substrate immediately after the laser irradiation. Accordingly, liposomes were fused under the microbubble, forming ultralong liposome tubes with a maximum length of more than 50 μm (Kojima et al., ACS Omega, 2022). We succeeded in direct observation of this phenomenon. This is a novel phenomenon that has never been reported before. We succeeded in observing fluorescent images of this phenomenon.