[19a-P02-1~10] 3.3 Biomedical optics

[19a-P02-2] In-vitroexperiments with biological phantom for cancer detection

〇(M1)Mike Raj Maskey¹, Asato Esumi¹, Nozomi Nishizawa¹ (1.Kitasato Univ.)

Keywords:

Circularly polarized light,Optical biopsy,Light scattering

The depolarization of circularly polarized light caused by scattering in biological tissues depends on the size of scatterer, that is the size of cell nuclei, which is useful for investigating the state of biological tissue. In this study, we prepared phantoms excluded the contribution of biological complexity, and investigate the optical response against irradiation of circularly polarized light to clarify the main cause of the depolarization in biological tissues. The phantoms prepared from UV resin and polystyrene beads shows the dependence of number density of beads on the depolarization of circularly polarized light, which indicates that they are ideal phantoms exhibiting good monodispersity.