[19p-B6-1~18] 12.3 Functional Materials and Novel Devices

2:45 PM - 3:00 PM JST(5:45 AM - 6:00 AM UTC)Presentation by Applicant for JSAP Young Scientists Presentation Award

[19p-B6-7] Sensing Performance of Electrochemical Aptamer-Based Sensors Using Thin-Film Gold Electrodes

〇(M1)Kento Terai¹, Kon Son^1,2, Toshinori Fujie¹ (1.Tokyo Tech, 2.UCSB)

Keywords:

Electrochemical Aptamer-Based (EAB) sensors,Real-time monitoring,Aptamer

Electrochemical Aptamer-Based (EAB) sensors are biosensors that utilize the DNA conformational change caused by the specific binding of methylene blue (MB)-modified DNA aptamer to target molecules. Since EAB sensors can monitor target molecules in vivo in real time, they are being applied to implantable sensors using gold wire electrodes as substrate. In this study, we aimed to fabricate thin-film gold electrodes that can be applied to biological tissues such as skin and evaluate their electrochemical properties for the development of wearable EAB sensors. Specifically, we evaluated the usefulness of various thin-film gold electrodes for EAB sensors by comparing the electrochemical properties of gold electrodes fabricated by Sputter or Thermal Evaporation (Therm. Evap.) and ink-jet printing (two types of Au ink, Au-J ink: gold nano-ink and Au-JB ink gold nano-ink with binder particles) with those of conventional gold wire electrodes.