Presentation Information

9:15 AM - 9:30 AM JST(12:15 AM - 12:30 AM UTC)Presentation by Applicant for JSAP Young Scientists Presentation Award

[23a-1BN-2]Sensitive detection of biomolecules by inclusion of gold nanocolloid in GUV

〇Yurika Inoue¹, Yuto Yoshinare¹, Akinobu Yamaguchi¹, Azusa Oshima², Masumi Yamaguchi², Akira Heya¹, Koji Sumitomo¹ (1.Univ. of Hyogo, 2.NTT Basic Res. Labs., BMC)

Keywords:

biosensor,surface-enhanced Raman scattering,Giant unilamellar vesicles

We propose the detection of molecules in giant vesicles (GUVs) by surface-enhanced Raman scattering by inclusion of gold nanocolloids in them. We confirmed the enhancement of Raman signals of target molecules (bipyridine) in GUVs. This result shows the possibility of sensitive detection of biomolecules, which are incorporated into GUVs by fusion of biological vesicles, using surface-enhanced Raman scattering, and is expected to be utilized as a biosensor.

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