Presentation Information

9:30 AM - 9:45 AM JST(12:30 AM - 12:45 AM UTC)

[25a-12E-3]Quantification of radicals in aqueous solution by positron lifetime: Experiment using a clinical PET system

〇Sodai Takyu¹, Ken-ichiro Matsumoto¹, Fumihiko Nishikido¹, Go Akamatsu¹, Hideaki Tashima¹, Miwako Takahashi¹, Taiga Yamaya¹ (1.QST)

Keywords:

Positron emission tomography,Quantum PET,Positron annihilation lifetime measurement

In a previous study, we observed that the positron lifetime changes depending on the radical concentration in an aqueous solution using a pair of PET detectors, and demonstrated the possibility of quantifying radicals in vivo. In this study, we investigated the relationship between quantifiable radical concentrations and statistics using a brain-dedicated PET system VRAIN. The results suggested that the difference in radical concentrations in aqueous solutions on the order of several mM can be quantified if the number of the obtained counts is larger than the eighth power of 10.

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