Presentation Information

[25p-11E-7]Microdetection of Nucleocapsid Proteins by Terahertz Chemical Microscopy

〇XUE DING1, Sayaka Tsuji1, Mana Murakami1, Jin Wang1, Hirofumi Inoue1, Toshihiko Kiwa1 (1.Okayama Univ)

Keywords:

Terahertz Chemical Microscopy,Nucleocapsid Proteins

In the last few years, the number of infected people worldwide has reached about 700 million and the number of deaths has been about 6.9 million. And the secondary infection rate reached 0.57-3.31%. Early detection of coronavirus increases the chance of healing the disease as well as reducing the transmission of the virus. PCR and antigen testing are commonly used to detect infection. PCR testing involves amplifying the RNA of a virus and analyzing its sequence that has high diagnostic accuracy but requires diagnostic time. Compared with PCR testing, antigen testing can diagnose within a few minutes and is widely used, but the probability of a positive diagnosis is around 80%. In this study, Detection of N proteins with a small volume was demonstrated by fabricating a sample well of 0.5 µl on a sensing plate of a terahertz chemical microscope (TCM).