[7p-N306-1~15] 12.6 Nanobiotechnology

2:15 PM - 2:30 PM JST(5:15 AM - 5:30 AM UTC)Presentation by Applicant for JSAP Young Scientists Presentation Award

[7p-N306-4] Cell-free and cell-based GFP synthesis and evaluation using mid-infrared pulsed laser

〇Yurito Takayama¹, Ryusei Sugawara¹, Jian Luo², Asuteka Nagao², Tutomu Suzuki², Hirohito Yamazaki¹ (1.Nagaoka Univ. of Tech., 2.The Univ. of Tokyo)

Keywords:

mid-infrared pulsed laser,protein synthesis,optical control

In recent years, spatiotemporal control of protein synthesis by light irradiation has attracted attention in the medical field. However, conventional methods have issues with the effects on biological functions associated with compound introduction and photoexcitation, as well as the time and cost required for molecular modification. In this study, we focus on the fact that mid-infrared light can directly excite molecular vibrations and causes little damage to biomolecules, and develop a label-free protein synthesis control method using a mid-infrared pulse laser.