Presentation Information
[7p-N322-6][JSAP-Optica Joint Symposia Invited Talk] Lensfree On-Chip Quantitative Phase Microscopy
〇Chao Zuo1 (1.Nanjing Univ of Science and Technology)
Keywords:
Quantitative Phase image
Lensfree on-chip digital holographic microscopy (LFOCDHM) is an emerging computational optical imaging technique that offers quantitative phase contrast, high space-bandwidth product, and a compact, lensless architecture. These advantages make it particularly attractive for high-throughput imaging in biomedical research, materials science, and industrial inspection. Unlike conventional diffraction-limited systems, the resolution of LFOCDHM is influenced by multiple factors, including the spatial and temporal coherence of illumination, sample-to-sensor distance, finite pixel size of the sensor, and the limited numerical aperture in angular diversity during reconstruction. In this talk, we present a systematic exploration of these parameters to construct a “pixel-resolution-limited” LFOCDHM system. Building upon this foundation, we introduce several pixel super-resolution techniques designed to overcome pixel-size limitations and enhance imaging resolution. Finally, we discuss the potential of integrating optical diffraction tomography into the lensfree on-chip imaging platform to enable high-throughput, 3D label free imaging.