[8p-N305-1~18] 12.7 Biomedical Engineering and Biochips

2:30 PM - 2:45 PM JST(5:30 AM - 5:45 AM UTC)Presentation by Applicant for JSAP Young Scientists Presentation Award

[8p-N305-5] Development of massively parallel biosensing technology for single cancer cell recognition

〇Tomoki Kato¹, Amer Akao¹, Toshiya Sakata¹ (1.Tokyo Univ.)

Keywords:

biosensor

Circulating tumor cells (CTCs), which are metastatic cancer cells found in the bloodstream, are significantly fewer in number compared to normal cells. This study aims to develop a biosensor capable of specifically detecting trace amounts of CTCs among a large population of cells. Specifically, we focus on ion-sensitive field-effect transistors (ISFETs) and aim to detect electrical signals resulting from captured cancer cells by immobilizing aptamers—molecules that selectively bind to cancer cell surface markers—onto the gate electrode surface.