[8p-N305-1~18] 12.7 Biomedical Engineering and Biochips

2:45 PM - 3:00 PM JST(5:45 AM - 6:00 AM UTC)Presentation by Applicant for JSAP Young Scientists Presentation Award

[8p-N305-6] Demonstration of an Aptamer Competitive Assay for Protein Detection Using Solution-Gated Thin-Film Transistors

〇Ken Takashima¹, Ritsu Naganuma¹, Toshiya Sakata¹ (1.tokyo univ)

Keywords:

Aptamer Competitive Assay,Solution Gate Transistor,Protein

This study aims to detect proteins such as glycated albumin (GA), a biomarker for diabetes. An aptamer with binding affinity for GA and a probe DNA with a complementary sequence are immobilized on the surface of an ITO channel. After the GA-aptamer reaction occurs in solution, the remaining aptamers hybridize with the probe DNA, enabling competitive and quantitative detection of GA.