Presentation Information

[9a-N103-2]Development of the imaging system to visualize the pharmacokinetics in small animals

〇(M2)Yuki Furukawa1,2, Maria Yamane1,2, Tadayuki Takahashi2, Shin'ichiro Takeda3,2, Miho Katsuragawa4,2, Hugo Allaire2, Shin Watanabe5, Takayoshi Kohmura1, Yuusuke Uchida1, Atsushi Ochiai6, Mayumi Hirakawa6, Hiroshi Mizuma7,8, Kazuhisa Ozeki9, Kei Higashikawa9, Miho Nagayasu9, Kimio Terao9 (1.Tokyo Univ. of Science, 2.Kavli IPMU, 3.F-REI, 4.Kyoto Univ., 5.ISAS/JAXA, 6.Tokyo Univ. of Science RIBS, 7.Osaka Metropolitan Univ., 8.QST, 9.Chugai Pharmaceutical)

Keywords:

collimator,pharmacokinetic imaging,CdTe semiconductor detector

We are developing an imaging system that achieves both high spatial resolution and low background, aiming to enable pharmacokinetic imaging that clearly distinguishes multiple radionuclides accumulated in small organs only a few millimeters in size of small animals. In this presentation, we report the results of imaging tests using the newly designed tungsten parallel-hole collimator, along with strategies for background reduction based on radiation simulations.