[10p-E204-1~13] 2.4 Life Sciences, Medical applications, Space and Earth Environment, Radiation Education

3:00 PM - 3:15 PM JST(6:00 AM - 6:15 AM UTC)Presentation by Applicant for JSAP Young Scientists Presentation Award

[10p-E204-6] High-Speed In Vivo Dynamic Imaging in Mice Using Scintillator-Based Photon-Counting CT

〇Takahiro Ro¹, Yuka Tsuchiya¹, Jun Kataoka¹, Makoto Arimoto², Hiroki Kawashima², Satoshi Kobayashi², Kenichiro Okumura², Naoki Ohno², Asuka Mizutani², Fitri Lucyana², Yu Furuta², Shuma Midorikawa², Shinsuke Terazawa³, Yuta Maeno³ (1.Waseda Univ., 2.Kanazawa Univ., 3.Proterial Ltd.)

Keywords:

PCCT,SiPM,scintillator

In this study, we developed a scintillator-based photon-counting CT system incorporating a large-area 2D sensor, a newly developed ASIC, and a bowtie filter, reducing the CT acquisition time from approximately 1 hour to 4.8 seconds. In vivo dynamic imaging was then performed in mice after intravenous injection of iodine and gadolinium contrast agents. Using K-edge imaging, we successfully visualized the transport process of the contrast agents in major vessels, the heart, kidneys, and liver.