Presentation Information
[11a-A31-5]Relationship Between Surface Properties and Epithelial Cell Adhesion of Nanodiamond Films
〇Yamato Ikiyama1, Hiroshi Naragino1, Itsuki Misono1, Lining Lou1, A.Z. Ahmed1, Tomohiro Yoshida2, Yohei Jinno3, Yasushige Sakamoto3, Ikiru Atsuta3, Yasunori Ayukawa3, Tsuyoshi Yoshitake1 (1.IGSES, Kyushu Univ., 2.Mechanics and Electronics Res. Inst., Fukuoka Ind. Technol. Cent., 3.Fac. Dent. Sci., Kyushu Univ.)
Keywords:
Nanodiamond Films,Surface Properties,Epithelial Cell Adhesion
Nanodiamond films were deposited on titanium substrates at room temperature by coaxial arc plasma deposition (CAPD), and the film surfaces were then treated with oxygen plasma. This study evaluated the relationship between the wettability of the nanodiamond film surface and the adhesion of oral epithelial cells (OECs). After oxygen plasma treatment, nanodiamond films exhibited superhydrophilicity with a water contact angle of less than 10°. The number of adherent OECs on the oxygen plasma-treated nanodiamond films increased approximately threefold compared with that on untreated titanium substrates. These results suggest that oxygen plasma treatment of nanodiamond films improves epithelial cell adhesion through changes in surface properties, including wettability. In this presentation, the chemical bonding state and surface charge state of the film surface will also be evaluated, and the influence of surface properties on epithelial cell adhesion will be discussed.