Presentation Information
[11a-PA4-8]Development and characterization of soft biological gel phantoms for latent cancer detection by circularly polarized light scattering
〇(B)Ran Togawa1, Iori Maeda2, Koki Kasama1, Mike Raj Maskey1, Nozomi Nshizawa1 (1.Sch. of Sci., Kitasato Univ., 2.Grad. Sch. of Med. Sci.)
Keywords:
Circularly polarized light,Optical biopsy,Cervical cancer
Cervical intraepithelial neoplasia generates at the bottom of the squamous epithelium, leading to the relatively low accuracy of early-stage diagnosis. However, the circularly polarized light scattering (CiPLS) method is, however, expected to evaluate the distribution of latent dysplasia because it enables the estimation of the content of abnormal cell nuclei in the scattering volume. To systematically assess the depth of latent cancer, we fabricate soft biological gel phantoms using an acrylamide gel as a substrate and verify the effectiveness of this method.