Presentation Information
[8a-PB1-32]Generation of reactive oxygen species using high-frequency, powerful ultrasound by lithium niobate transducer and the photocatalytic reaction of titanium dioxide nanoparticles
〇(DC)Kotaro Fujishiro1, Satoshi Okada2, Takahiro Kuchimaru3, Yuta Kurashina1 (1.Tokyo Univ. of Agriculture and Technology, 2.Inst. of Science Tokyo, 3.Jichi Medical Univ.)
Keywords:
ultrasound,sonochemistry,photocatalytic reaction
Reactive oxygen species (ROS) generated by ultrasound irradiation are used in cancer therapy because ROS induce cell death. Previously, ROS generation in both solutions and cells has been reported by our group using high-frequency, powerful ultrasound generated by a lithium niobate transducer. However, ROS generation in solution was insufficient for effective cancer therapy. In this study, we amplified ROS generation in solution by combining high-frequency, powerful ultrasound with the photocatalytic reaction of titanium dioxide nanoparticles.